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Osteoarthritis

Osteoarthritis is the most common joint condition worldwide, and its burden is growing as ageing populations and high rates of sedentary work accelerate its prevalence. It occurs when the cartilage cushioning the ends of bones gradually wears down, leaving the underlying bone exposed and inflamed.

Voltaren

Diclofenac

50 · 100mg

Diclofenac 50mg and 100mg tablets, used for rheumatoid arthritis, osteoarthritis and acute musculoskeletal pain. A phenylacetic acid NSAID.

From$0.36/ tabletView

Celebrex

Celecoxib

100 · 200mg

Celecoxib 100mg and 200mg hard capsules, used for osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. A selective COX-2 inhibitor.

From$0.57/ tabletView

Arcoxia

Etoricoxib

60 · 90 · 120mg

Etoricoxib 60mg, 90mg and 120mg film-coated tablets, used for osteoarthritis, rheumatoid arthritis and gouty arthritis. A selective COX-2 inhibitor.

From$0.67/ tabletView

Naprosyn

Naproxen

250 · 500mg

Naproxen 250mg and 500mg, as plain and gastro-resistant tablets, used for rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.

From$0.55/ tabletView

Indocin

Indometacin

25 · 50 · 75mg

Indometacin 25mg, 50mg and 75mg capsules and suppositories, used for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and acute gout.

From$0.32/ tabletView

Mobic

Meloxicam

7.5 · 15mg

Meloxicam 7.5mg and 15mg tablets, used for osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. An oxicam that leans towards COX-2.

From$0.33/ tabletView

Voveran

Diclofenac

50mg

Voveran is diclofenac 50mg in a gastro-resistant tablet, so it passes the stomach before dissolving. Listed for arthritis and ankylosing spondylitis.

From$0.39/ tabletView

Voveran SR

Diclofenac

100mg

Voveran SR is diclofenac 100mg in a prolonged-release tablet for rheumatoid arthritis and osteoarthritis, releasing the NSAID gradually.

From$0.94/ tabletView

Voltaren SR

Diclofenac

100mg

Voltaren SR is diclofenac 100mg in a modified-release tablet for rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.

From$0.64/ tabletView

Aceclofenac Tablets

Aceclofenac

100 · 200mg

Aceclofenac 100mg and 200mg tablets, an NSAID used for rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Cyclooxygenase is the target.

From$0.38/ tabletView

Feldene

Piroxicam

10 · 20mg

Piroxicam 10mg and 20mg hard capsules, used for osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. An oxicam NSAID taken by mouth.

From$0.52/ tabletView

Anaprox

Naproxen

500mg

Naproxen 500mg tablets, used for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and musculoskeletal pain. A propionic acid NSAID.

From$0.69/ tabletView

Voltarol

Diclofenac

100mg

Diclofenac at the single 100mg tablet strength, used for osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. A cyclooxygenase inhibitor.

From$0.51/ tabletView

Naprelan

Naproxen

250 · 500mg

Naprelan is naproxen 250mg and 500mg in a prolonged-release tablet for rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.

From$0.66/ tabletView

Lodine

Etodolac

200 · 300 · 400mg

Etodolac 200mg, 300mg and 400mg tablets and capsules, used for osteoarthritis, rheumatoid arthritis and pain. An NSAID of the acetic acid group.

From$0.72/ tabletView

Key points

  • The cushioning cartilage at joint ends thins with time, exposing and irritating the bone underneath.
  • Discomfort tends to start mild and worsen with use, and stiffness on waking generally clears within roughly thirty minutes.
  • Gentle activities that avoid heavy joint loading, such as swimming or cycling, are regarded as the strongest long-term protective measure.
  • Anti-inflammatory painkillers are the medicine class reached for most often once activity and weight control are not enough alone.

How joints are affected

The knees, hips, and hands bear the brunt of most cases, though any joint can be involved. Pain typically builds slowly, a dull ache at first, deepening to sharper discomfort after activity. Morning stiffness usually eases within 30 minutes, which helps distinguish osteoarthritis from inflammatory conditions like rheumatoid arthritis. Swelling, a grating sensation (crepitus), and a reduced range of motion are common as the condition progresses.

Risk rises with age, excess body weight, prior joint injury, and repetitive occupational strain. Women are more commonly affected, especially after the menopause.

Managing pain and slowing the impact

Exercise remains the single most effective long-term intervention: low-impact activities such as swimming, cycling, and tai chi preserve muscle support around the joint without adding load. Weight loss where relevant can meaningfully reduce knee and hip stress.

For pain relief, non-steroidal anti-inflammatory drugs (NSAIDs) are the most widely used class. Options in our pain management range include diclofenac, naproxen, meloxicam, and celecoxib, a COX-2 selective agent often chosen when gastrointestinal tolerability is a concern. Piroxicam and indometacin are longer-established alternatives still widely used.

Topical diclofenac gel is an option for localised knee or hand pain, delivering anti-inflammatory effect with less systemic exposure than oral tablets.

If joint pain is severe, rapidly worsening, or accompanied by significant swelling and warmth, a clinical assessment is advisable to rule out other causes and discuss further options.

Further reading