Combigan

Brimonidine · Timolol

Product utilizes brimonidine and timolol, indicated to lower intraocular pressure and designed to support the treatment of glaucoma or ocular hypertension.

Category
Eye Care
Active ingredients
Brimonidine · Timolol
Supply
Pharmacy
Route
Ocular use
Form
Eye drops, solution
Strengths
0.2/0.5%

Combigan details

Therapeutic class
Alpha-Adrenergic Agonist/Beta-Blocker
Pharmacological class
Alpha-2 Adrenergic Agonist; Beta-Blocker
Minor side effects
eye redness; burning sensation; stinging; eye irritation; dizziness
Moderate side effects
conjunctivitis; blepharitis; visual disturbance; superficial punctate keratitis
Dosage forms
Eye drops, solution
Administration route
Ocular use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
AbbVie
Onset Time
30–60 minutes
Duration
12–24 hours
Age restrictions
Not for use in children or adolescents.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary. Breastfeeding: Not recommended.
Contraindications

hypersensitivity to brimonidine; hypersensitivity to timolol; bronchial asthma; severe chronic obstructive pulmonary disease; sinus bradycardia; second or third degree atrioventricular block; cardiogenic shock

Precautions and warnings

monitor for heart rate changes; use with caution in patients with cardiovascular disease; may cause drowsiness

Serious side effects

anaphylaxis, requires immediate medical attention; bronchospasm, requires immediate medical attention; heart failure, requires immediate medical attention

Patient summary

Product utilizes brimonidine and timolol, indicated to lower intraocular pressure and designed to support the treatment of glaucoma or ocular hypertension.

Mechanism of action

This medicine works by reducing the production of fluid in the eye and increasing the drainage of eye fluid, which lowers pressure within the eye to healthy levels.

Storage instructions

Store at room temperature in a tightly closed container, away from moisture and direct light.

Drug interactions

beta-blockers; calcium channel blockers; digitalis glycosides; catecholamine-depleting drugs

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Combigan

Combigan incorporates Brimonidine and Timolol, a combination used to manage glaucoma and ocular hypertension. Manufactured by AbbVie, the product is supplied in a bottle at 0.2/0.5% strength. It is a preferred choice for individuals seeking a standard, consistent approach to managing intraocular pressure levels.

Buying Combigan online

Combigan is registered across 14 markets including Taiwan, South Korea and Japan, with availability also in the UAE, Singapore and Hong Kong. For expats and people across the region, finding specific ophthalmic solutions can be a challenge. We make Combigan one of the most ordered items across our network, helping patients access their treatment with ease, whether they are living or travelling in Asia.