Casodex
Designed to target tumour growth, indicated to manage advanced prostate cancer effectively.
- Category
- Oncology Support
- Active ingredient
- Bicalutamide
- Supply
- Rx
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 50mg
Casodex details
- Condition
- Advanced Prostate Cancer
- Therapeutic class
- Anti-Androgen
- Pharmacological class
- Non-steroidal Anti-Androgen
- Contraindications
- hypersensitivity to bicalutamide; pregnancy; women
- Precautions and warnings
- monitor liver function regularly; not indicated for use in children
- Minor side effects
- hot flushes; nausea; fatigue; constipation
- Moderate side effects
- gynaecomastia; breast tenderness; elevated liver enzymes
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- AstraZeneca
- Onset Time
- 4–8 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 30°C.
- Drug interactions
- warfarin; ciclosporin
- Age restrictions
- Not for use in patients under 18.
- Pregnancy and breastfeeding
- Pregnancy: Not applicable (contraindicated). Breastfeeding: Not applicable.
Serious side effects
hepatitis, requires immediate medical attention; cholestasis, requires immediate medical attention
Patient summary
Designed to target tumour growth, indicated to manage advanced prostate cancer effectively.
Mechanism of action
Bicalutamide is a non-steroidal anti-androgen that binds to the androgen receptor. It prevents the binding of testosterone and dihydrotestosterone, thereby inhibiting the growth and progression of androgen-sensitive prostate cancer cells.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Casodex
Casodex serves as a primary treatment for the management of advanced prostate cancer, utilizing bicalutamide as its active ingredient. This medication is produced by AstraZeneca and is supplied as 50mg tablets, offering a standard therapeutic choice for individuals managing this condition.
Casodex availability in Asia
Casodex is registered across 14 markets, including the UAE, Singapore and Hong Kong, with further availability in Thailand, Malaysia and the Philippines. Generic bicalutamide, notably manufactured in India, is often more affordable than the original brand for expats and people residing at a distance from a well-stocked medical outlet. This medication is best used under the direct care of a doctor.