Valtrex

Valaciclovir

Indicated to manage herpes zoster and herpes simplex virus infection to alleviate painful outbreaks and speed recovery.

Category
Antivirals
Active ingredient
Valaciclovir
Supply
Pharmacy
Route
Oral use
Form
Film-coated tablet
Strengths
500 · 1000mg

Valtrex details

Therapeutic class
Antiviral Agent
Pharmacological class
Nucleoside analogue
Contraindications
hypersensitivity to valaciclovir
Precautions and warnings
maintain adequate fluid intake; use with caution in elderly patients
Minor side effects
headache; nausea
Moderate side effects
dizziness; abdominal pain
Dosage forms
Film-coated tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
GSK
Onset Time
1–2 hours
Duration
8–12 hours
Storage instructions
Store at room temperature.
Drug interactions
nephrotoxic agents
Age restrictions
Dose adjustment required for patients with renal impairment and the elderly.
Serious side effects

renal impairment, requires immediate medical attention; neurological symptoms, requires immediate medical attention

Patient summary

Indicated to manage herpes zoster and herpes simplex virus infection to alleviate painful outbreaks and speed recovery.

Mechanism of action

Valaciclovir is a prodrug of acyclovir. It is converted rapidly to acyclovir in the body, which selectively inhibits viral DNA polymerase, thereby interrupting DNA synthesis in herpes viruses.

Pregnancy and breastfeeding

Pregnancy: Use only if clearly needed. Breastfeeding: Use with caution; monitor the infant.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Valtrex

Valtrex is the primary brand name for valaciclovir, an antiviral used in the management of Herpes Zoster, Herpes Simplex and Genital Herpes. Produced by GSK, this treatment comes as a tablet available in 500mg and 1000mg strengths. It assists in inhibiting viral replication to reduce the duration of outbreaks.

Valtrex availability in Asia

Valtrex is registered across 14 markets including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Indonesia and Taiwan. Generic valaciclovir, often manufactured in India, offers a cost-effective alternative to the original GSK product for patients managing these viral conditions. For expats or travellers in regions where local supply can be inconsistent, these options support consistent therapeutic management. This medication is best used under a doctor’s care for proper monitoring.