Baraclude

Entecavir

Developed to manage chronic hepatitis b infection to alleviate viral replication.

Category
Antivirals
Active ingredient
Entecavir
Supply
Pharmacy
Route
Oral use
Form
Film-coated tablet
Strengths
0.5mg

Baraclude details

Therapeutic class
Hepatitis B Antiviral
Pharmacological class
Nucleoside Analogue
Contraindications
hypersensitivity to entecavir
Minor side effects
headache; fatigue
Moderate side effects
dizziness; nausea
Dosage forms
Film-coated tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Bristol-Myers Squibb
Onset Time
varies
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
drugs affecting renal function
Pregnancy and breastfeeding
Pregnancy: use only if clearly necessary. Breastfeeding: not recommended.
Precautions and warnings

risk of lactic acidosis; severe acute exacerbations of hepatitis upon discontinuation; monitor renal function

Serious side effects

lactic acidosis, requires immediate medical attention; severe hepatomegaly with steatosis, requires immediate medical attention

Patient summary

developed to manage chronic hepatitis b infection to alleviate viral replication.

Mechanism of action

Inhibits hepatitis B virus polymerase, which interferes with the viral replication process.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Baraclude

Baraclude is a medication containing the active ingredient Entecavir, utilised for the management of Chronic Hepatitis B. Manufactured by Bristol-Myers Squibb, it is provided as a tablet in a strength of 0.5mg. It functions by inhibiting viral replication, assisting in controlling the virus to help maintain liver health over the long term.

Baraclude availability in Asia

Baraclude comprises a registered presence across 14 markets including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Indonesia and Taiwan. While the original brand is well-regarded, generic Entecavir is often more affordable for individuals living in areas where consistent medical supply is limited. Given the long-term nature of this condition, this treatment is most effective when used under the guidance of a medical professional.