Harvoni
Indicated for chronic hepatitis c to support viral clearance.
- Category
- Antivirals
- Active ingredients
- Ledipasvir · Sofosbuvir
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 90/400mg
Harvoni details
- Condition
- Chronic Hepatitis C
- Therapeutic class
- Hepatitis C Antiviral
- Pharmacological class
- NS5A Inhibitor; NS5B Polymerase Inhibitor
- Contraindications
- hypersensitivity to ledipasvir; hypersensitivity to sofosbuvir
- Minor side effects
- fatigue; headache
- Moderate side effects
- insomnia; nausea
- Serious side effects
- hypersensitivity, requires immediate medical attention
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Patient summary
- Indicated for chronic hepatitis c to support viral clearance.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Gilead Sciences
- Onset Time
- 1–2 weeks
- Duration
- 12–24 weeks
- Storage instructions
- Store below 30°C in the original container.
- Drug interactions
- amiodarone; rifampicin
- Age restrictions
- For adult use.
Mechanism of action
A combination of a direct-acting antiviral drug that inhibits NS5A and an NS5B polymerase inhibitor, used to stop the hepatitis C virus from reproducing in the body.
Pregnancy and breastfeeding
Pregnancy: Use only if the potential benefit justifies potential risk. Breastfeeding: Advise that the excretion of components into human milk is unknown.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Harvoni
Harvoni is an antiviral medication containing ledipasvir and sofosbuvir, formulated by Gilead Sciences for the treatment of chronic hepatitis C. Supplied as a 90/400mg tablet, it is designed to inhibit viral replication within the body. This specialised therapy provides a targeted approach for those managing this particular viral condition.
Harvoni availability in Asia
Harvoni is registered across 14 markets including Singapore, Hong Kong and Thailand, with availability also found in Malaysia, the Philippines and Indonesia. Generic ledipasvir and sofosbuvir, much of which is made in India, serves as a far more affordable alternative for expats and those living far from a reliable pharmacy that stocks the original brand. This treatment is best used under a doctor’s care to manage individual health requirements.