Toprol Xl
Developed to target cardiac excitability, reducing workload on the heart.
- Category
- Heart & Blood Pressure
- Active ingredient
- Metoprolol
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Modified-release tablet
- Strengths
- 25 · 50 · 100mg
Toprol Xl details
- Conditions
- Hypertension · Angina Pectoris · Myocardial Infarction Prophylaxis
- Alternative names
- Betaloc SA; Lopresor
- Therapeutic class
- Beta Blocker
- Pharmacological class
- Beta-1 blocker
- Minor side effects
- fatigue; dizziness; cold extremities
- Moderate side effects
- bradycardia; sleep disturbances; depression
- Dosage forms
- Modified-release tablet
- Administration route
- Oral use
- Patient summary
- developed to target cardiac excitability, reducing workload on the heart.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- AstraZeneca
- Onset Time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C in a dry place.
- Drug interactions
- calcium channel blockers; cimetidine
- Age restrictions
- Safe for use in children with specific monitoring.
Contraindications
hypersensitivity to beta blockers; bradycardia; severe asthma; uncompensated heart failure
Precautions and warnings
do not stop taking abruptly; may mask signs of hypoglycaemia; report shortness of breath immediately
Serious side effects
heart block, requires immediate medical attention; bronchospasm, requires immediate medical attention
Mechanism of action
Toprol Xl is a cardioselective beta-1 receptor blocker. By preventing catecholamine binding at these receptor sites in the heart, it lowers the force and rate of myocardial contraction and reduces blood pressure, decreasing the heart's oxygen demand.
Pregnancy and breastfeeding
Pregnancy: Use only if benefits justify risks. Breastfeeding: Monitor nursing infant for potential pharmacological effects.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Toprol Xl
Toprol Xl contains metoprolol, a beta-blocker used for managing hypertension, angina pectoris and myocardial infarction prophylaxis. The same active ingredient is also marketed under brands like Betaloc Sa and Lopresor. Produced by AstraZeneca, this medication is available as a tablet in strengths of 25mg, 50mg and 100mg.
Buying Toprol Xl online
Toprol Xl is registered across 13 markets including South Korea, Japan and the UAE, with distribution also supported in Singapore, Hong Kong and Thailand. Because generic metoprolol is substantially more affordable than the original brand, this is one of the most ordered medications for expats and residents across the region who require consistent access to their maintenance therapy. This product can be ordered online for delivery within these jurisdictions.