Tivicay
Indicated for human immunodeficiency virus infection to alleviate viral load.
- Category
- HIV Management
- Active ingredient
- Dolutegravir
- Supply
- Rx
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 50mg
Tivicay details
- Condition
- HIV Infection
- Therapeutic class
- Integrase Strand Transfer Inhibitor (INSTI)
- Pharmacological class
- Integrase Inhibitor
- Contraindications
- hypersensitivity to dolutegravir; concurrent use of dofetilide
- Minor side effects
- insomnia; headache; fatigue; nausea
- Moderate side effects
- elevated liver enzymes; rash
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Patient summary
- indicated for human immunodeficiency virus infection to alleviate viral load.
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- ViiV Healthcare
- Onset Time
- 1–2 hours
- Duration
- 24 hours
- Storage instructions
- Store in the original container to protect from moisture.
- Drug interactions
- metformin; antacids; calcium supplements
Precautions and warnings
monitor for hypersensitivity reactions; observe for signs of immune reconstitution syndrome; use with caution in hepatic impairment
Serious side effects
severe hypersensitivity reaction, requires immediate medical attention; suicidal ideation, requires immediate medical attention
Mechanism of action
This agent acts by inhibiting the strand transfer activity of the HIV integrase enzyme, a critical protein required for viral replication. By blocking the integration of the viral genome into host cell DNA, it suppresses viral proliferation.
Age restrictions
Applicable for use in children and adults depending on weight/age thresholds specified by the prescriber.
Pregnancy and breastfeeding
Pregnancy: Use may be considered after clinical evaluation. Breastfeeding: Not recommended due to potential transmission.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Tivicay
Tivicay is an antiretroviral medication containing the active ingredient dolutegravir, used in the management of HIV infection. Produced by ViiV Healthcare, this therapy is supplied as a tablet at a 50mg strength. It remains a consistent option for individuals following a specific regimen to maintain their ongoing health requirements.
Tivicay availability in Asia
Tivicay is registered across 14 markets, including Singapore, Hong Kong and Thailand, with availability also in Malaysia, the Philippines and Indonesia. While the original brand is established, generic dolutegravir, much of it made in India, is far more affordable for expatriates and people living far from a fully stocked pharmacy. This medication is best used under the specific care of a doctor.