Zepdon

Raltegravir

Indicated to target viral replication in HIV management formulated to mitigate disease progression.

Active ingredient
Raltegravir
Supply
Rx
Route
Oral use
Form
Tablet
Strengths
400mg

Zepdon details

Condition
HIV Infection
Alternative names
Isentress
Therapeutic class
Integrase Inhibitor
Pharmacological class
Integrase Inhibitor
Contraindications
hypersensitivity to raltegravir
Precautions and warnings
monitor for muscle pain; report any signs of rash
Minor side effects
headache; fatigue; nausea
Moderate side effects
insomnia; abdominal pain
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Natco Pharma
Onset Time
1–2 hours
Duration
12 hours
Storage instructions
Store at room temperature in a dry place.
Drug interactions
Rifampicin; Antacids
Age restrictions
Suitable for adolescents and adults.
Serious side effects

rhabdomyolysis, requires immediate medical attention; severe skin hypersensitivity reactions, requires immediate medical attention

Patient summary

Indicated to target viral replication in HIV management formulated to mitigate disease progression.

Mechanism of action

Raltegravir is an HIV-1 integrase strand transfer inhibitor that blocks the insertion of HIV DNA into the human genome, preventing the virus from replicating in host cells.

Pregnancy and breastfeeding

Pregnancy: Use recommended by specialist only. Breastfeeding: Advise against breastfeeding due to potential viral transmission.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Zepdon

Zepdon contains raltegravir, an antiretroviral medication used to manage HIV infection. Widely known under the brand name Isentress, this integrase inhibitor is supplied as a 400mg tablet. Natco Pharma manufactures this version to offer a consistent, quality-assured alternative for patients requiring reliable access to their ongoing antiretroviral therapy.

Zepdon availability in Asia

Zepdon is registered across 13 markets including Thailand, Malaysia and the Philippines, with availability also in Indonesia, Taiwan and South Korea. Generic raltegravir, much of it made in India, is far more affordable than the original brand, providing an important access route for expats and others living far from a well-stocked pharmacy or specialist service. As with all antiretroviral treatments, this medicine is best used under the regular supervision of a doctor.