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HIV Infection

HIV (Human Immunodeficiency Virus) targets CD4 immune cells, gradually weakening the body’s defences if left untreated. With modern antiretroviral therapy (ART), HIV is a manageable chronic condition rather than a fatal one. People on effective treatment achieve undetectable viral loads, stay well, and cannot transmit the virus sexually.

Triumeq

Abacavir, Dolutegravir, Lamivudine

600/50/300mg

Abacavir, dolutegravir and lamivudine in one tablet, used in the management of HIV infection. Three agents against three stages of the viral cycle.

From$8.69/ tabletView

Tivicay

Dolutegravir

50mg

Dolutegravir 50mg film-coated tablets, used in the management of HIV infection. An integrase inhibitor that blocks the strand transfer step.

From$2.74/ tabletView

Kaletra

Lopinavir, Ritonavir

200/50mg

Lopinavir with ritonavir as a 200/50mg film-coated tablet, used in the management of HIV infection. A protease inhibitor with its pharmacokinetic booster.

From$4.98/ tabletView

Epivir

Lamivudine

150mg

Lamivudine 150mg film-coated tablets, used in the management of HIV infection and chronic hepatitis B. A nucleoside analogue acting on reverse transcriptase.

From$1.53/ tabletView

Isentress

Raltegravir

400mg

Raltegravir 400mg film-coated tablets, used in the management of HIV infection. An integrase strand transfer inhibitor, blocking the enzyme the virus needs.

From$7.29/ tabletView

Sustiva

Efavirenz

200 · 600mg

Efavirenz 200mg and 600mg film-coated tablets, used in the management of HIV infection. An NNRTI that binds reverse transcriptase directly.

From$3.87/ tabletView

Viramune

Nevirapine

200mg

Nevirapine 200mg tablets, used in the management of HIV infection. An NNRTI that binds reverse transcriptase directly rather than as a substrate.

From$3.60/ tabletView

Ziagen

Abacavir

300mg

Abacavir 300mg film-coated tablets, used in the management of HIV infection. A nucleoside analogue reverse transcriptase inhibitor.

From$7.03/ tabletView

Zepdon

Raltegravir

400mg

Zepdon is raltegravir 400mg tablets for HIV infection, an integrase strand transfer inhibitor that keeps viral DNA out of the host genome.

From$6.80/ tabletView

Darunavir Tablets

Darunavir

600 · 800mg

Darunavir 600mg and 800mg film-coated tablets, used in the management of HIV infection. A protease inhibitor that halts assembly of new virus.

From$9.35/ tabletView

Combivir

Lamivudine, Zidovudine

300/150mg

Lamivudine with zidovudine as a 300/150mg film-coated tablet, used in the management of HIV infection. Two nucleoside reverse transcriptase inhibitors.

From$1.60/ tabletView

Tenofovir

Tenofovir

300mg

Tenofovir disoproxil 300mg tablets, used in the management of HIV infection and chronic hepatitis B. It terminates the growing DNA chain.

From$5.30/ tabletView

Key points

  • Early infection often causes a brief flu-like illness, after which the virus enters a long silent phase.
  • Left untreated, the immune system weakens progressively until the body becomes vulnerable to infections it would normally fight off.
  • Effective control relies on pairing medicines from several different classes, taken continuously since pausing allows the virus to resurge.

How the virus progresses

After initial infection, many people experience a short flu-like illness (fever, swollen glands, sore throat) that resolves on its own. The virus then enters a long silent phase during which CD4 counts slowly fall. Without treatment, this eventually leads to AIDS, a stage defined by severe immune suppression and opportunistic infections.

Antiretroviral treatment

ART combines medicines from different drug classes to suppress the virus below detectable levels. Common backbone agents include lamivudine, abacavir, and zidovudine, paired with integrase inhibitors such as dolutegravir or raltegravir, or the non-nucleoside agent efavirenz. Treatment is lifelong; stopping allows the virus to rebound. The full range of available regimens is listed in the HIV management category, which sits within the broader antivirals section.

When to seek urgent care

Sudden severe headache, stiff neck, confusion, difficulty breathing, or unexplained rapid weight loss in someone with HIV warrant same-day medical attention, as these can signal opportunistic infections that need prompt treatment.

Further reading