Prograf
Designed to mitigate transplant rejection to support long-term organ health.
- Category
- Autoimmune Support
- Active ingredient
- Tacrolimus
- Route
- Oral use
- Form
- Capsule, hard
- Strengths
- 0.5 · 1 · 5mg
You will receive a quality generic equivalent, depending on stock.
Prescription rules on Prograf vary by country.
Prograf details
- Condition
- Transplant Rejection
- Alternative names
- Adoport
- Therapeutic class
- Immunosuppressant
- Pharmacological class
- Calcineurin Inhibitor
- Contraindications
- hypersensitivity to tacrolimus; hypersensitivity to macrolides
- Minor side effects
- tremor; headache
- Moderate side effects
- hypertension; renal impairment; abnormal liver function tests
- Dosage forms
- Capsule, hard
- Administration route
- Oral use
- Patient summary
- Designed to mitigate transplant rejection to support long-term organ health.
- Supply category
- Prescription only (specially controlled medicine)
- Originator
- Astellas Pharma
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store in the original blister package.
- Drug interactions
- grapefruit; ketoconazole; rifampicin
- Age restrictions
- Adjusted for weight in paediatric patients.
Precautions and warnings
regular blood monitoring required; avoid excessive sun exposure; monitor kidney function
Serious side effects
opportunistic infections, requires immediate medical attention; lymphoma, requires immediate medical attention
Mechanism of action
Suppresses the immune response by inhibiting calcineurin, thereby preventing the activation of T-cells that trigger organ rejection.
Pregnancy and breastfeeding
Pregnancy: Avoid unless deemed essential by a specialist. Breastfeeding: Not recommended.
What you will receive
Prograf is the originator brand name, made by Astellas Pharma. We use it here to identify the medicine only; we are not affiliated with Astellas Pharma and do not ship the original Prograf.
- You receive a generic equivalent: the same active ingredient (Tacrolimus) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Prograf
Prograf is a well-known brand of tacrolimus, a medication used to prevent organ transplant rejection. The same active ingredient is also marketed as Adoport. This medicine is supplied as a tablet in strengths of 0.5mg, 1mg, and 5mg to assist in maintaining immune system stability following transplant surgery.
Prograf availability in Asia
Prograf is registered across 14 markets, including South Korea, Japan and the UAE, with availability also in Singapore, Hong Kong and Thailand. While generic tacrolimus, often produced in India, provides a more affordable alternative to the original brand, sourcing reliable medication remains a priority for expats and residents across these regions. This medicine is best used under the regular supervision of a transplant specialist to ensure proper clinical management.