Pradaxa
Intended to alleviate the risk of stroke and systemic embolism in atrial fibrillation.
- Category
- Heart & Blood Pressure
- Active ingredient
- Dabigatran
- Supply
- Rx
- Route
- Oral use
- Form
- Capsule, hard
- Strengths
- 150mg
Pradaxa details
- Conditions
- Atrial Fibrillation · Venous Thromboembolism
- Therapeutic class
- Direct Thrombin Inhibitor
- Pharmacological class
- Direct Oral Anticoagulant (DOAC)
- Minor side effects
- dyspepsia; abdominal pain; nausea
- Moderate side effects
- anaemia; gastritis
- Dosage forms
- Capsule, hard
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Boehringer Ingelheim
- Onset Time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store in original bottle; keep tightly closed and away from moisture.
- Drug interactions
- rifampicin; verapamil; amiodarone
- Age restrictions
- Not for use in children.
Contraindications
hypersensitivity to dabigatran; severe renal impairment; active bleeding; mechanical prosthetic heart valve
Precautions and warnings
risk of haemorrhage, monitor for bleeding; use caution in patients with history of gastrointestinal disease; do not chew or open capsules
Serious side effects
major haemorrhage, requires immediate medical attention; gastrointestinal bleeding, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
intended to alleviate the risk of stroke and systemic embolism in atrial fibrillation.
Mechanism of action
It acts as a potent, competitive, direct thrombin inhibitor. By blocking thrombin, it prevents the conversion of fibrinogen to fibrin, thereby inhibiting clot formation in the bloodstream.
Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Breastfeeding should be stopped during treatment.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Pradaxa
Pradaxa is the original brand of dabigatran, an anticoagulant used for the management of Atrial Fibrillation and Venous Thromboembolism. Developed by Boehringer Ingelheim, the treatment is supplied as a capsule in 150mg strength. Patients rely on this medication to maintain stable health profiles whilst living in or travelling through the region.
Buying Pradaxa online
Pradaxa is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. Generic dabigatran, much of it made in India, is often available as a more affordable alternative to the original brand, providing reliable access for expats living far from a well-stocked pharmacy. Ordering online through ZoneMD enables patients to maintain their daily regimen consistently across the region.