Motegrity
Developed to target chronic constipation where laxatives fail, this medication is utilized to support bowel regularity and to alleviate intestinal discomfort.
- Category
- Digestive Health
- Active ingredient
- Prucalopride
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 2mg
Motegrity details
- Condition
- Chronic Constipation
- Alternative names
- Resolor
- Therapeutic class
- Serotonin (5-HT4) Receptor Agonist
- Pharmacological class
- 5-HT4 Agonist
- Precautions and warnings
- monitor for severe diarrhoea; use caution in cardiac patients
- Minor side effects
- headache; nausea; diarrhoea; abdominal pain
- Moderate side effects
- dizziness; flatulence; fatigue
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Shire
- Onset Time
- 1–2 hours
- Duration
- 24 hours
- Storage instructions
- Store in a cool, dry place.
- Drug interactions
- atropine; erythromycin
- Age restrictions
- Not for use in children under 18.
- Pregnancy and breastfeeding
- Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications
hypersensitivity; severe renal impairment; intestinal perforation; severe inflammatory diseases of the intestinal tract
Serious side effects
tachycardia, requires immediate medical attention; palpitations, requires immediate medical attention
Patient summary
Developed to target chronic constipation where laxatives fail, this medication is utilized to support bowel regularity and to alleviate intestinal discomfort.
Mechanism of action
Prucalopride is a high-affinity 5-HT4 receptor agonist that stimulates colonic motility, thereby increasing bowel movement frequency and reducing the symptoms of chronic constipation.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Motegrity
Motegrity is a medication containing prucalopride, used to manage chronic constipation in adults when standard laxatives fail to provide relief. The same active ingredient is known globally as Resolor, produced by Shire and supplied as 2mg tablets. Consistent use supports regular bowel function for those struggling with long-term digestive motility issues.
Buying Motegrity online
Motegrity is registered across 13 markets including Japan, the UAE and Singapore, with availability extending to Hong Kong, Thailand and Malaysia. As a targeted treatment for digestive health, the medication is frequently ordered online for delivery across the region. Expats and residents who require consistent access to their established regimen often find that online procurement provides a reliable way to maintain their treatment cycle without the uncertainty of local pharmacy stock levels.