Mestinon

Pyridostigmine

Formulated to address muscle weakness, utilized to support neuromuscular transmission and to relieve fatigue in myasthenia gravis.

Category
Neurology
Active ingredient
Pyridostigmine
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
60mg

Mestinon details

Therapeutic class
Acetylcholinesterase Inhibitor
Pharmacological class
Parasympathomimetic
Contraindications
mechanical intestinal obstruction; urinary tract obstruction; hypersensitivity
Minor side effects
nausea; abdominal cramps; diarrhoea
Moderate side effects
bradycardia; bronchial secretions; muscle fasciculations
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Meda
Onset Time
30–60 minutes
Duration
4–6 hours
Storage instructions
Store at room temperature in a dry place.
Drug interactions
beta-blockers; aminoglycosides
Age restrictions
Suitable for children and adults under specialist guidance.
Precautions and warnings

caution in patients with asthma; monitor for cholinergic crisis; use with care in patients with bradycardia

Serious side effects

cholinergic crisis, requires immediate medical attention; convulsions, requires immediate medical attention

Patient summary

Formulated to address muscle weakness, utilized to support neuromuscular transmission and to relieve fatigue in myasthenia gravis.

Mechanism of action

Pyridostigmine inhibits the enzyme acetylcholinesterase, which breaks down acetylcholine at the neuromuscular junction, thereby increasing the availability of acetylcholine to stimulate muscle contraction.

Pregnancy and breastfeeding

Pregnancy: Use only when strictly necessary. Breastfeeding: Small amounts excreted; monitor infant.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Mestinon

Mestinon is the established brand name for pyridostigmine, a treatment used to support better muscle function for patients managing Myasthenia Gravis. Manufactured by Meda, this medication is supplied as a 60mg tablet. Supporting the connection between nerves and muscles helps to manage the symptoms associated with the condition.

Buying Mestinon online

Mestinon is registered across 14 markets, including Thailand, Malaysia and the Philippines, with availability also in Indonesia, Taiwan and South Korea. As Myasthenia Gravis requires consistent daily management, regular access to medicine is a priority for expats living across the region. Generic pyridostigmine, often sourced from India, is far more affordable than the branded version. We provide access to this essential therapy, ensuring that patients across these areas can maintain their routine reliably and affordably.