Lioresal
Designed to relieve muscle spasms to support motor function.
- Category
- Pain Management
- Active ingredient
- Baclofen
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet; Oral solution
- Strengths
- 10 · 25mg
Lioresal details
- Conditions
- Multiple Sclerosis · Spinal Cord Injury · Spinal Cord Spasm
- Therapeutic class
- Muscle Relaxant
- Pharmacological class
- GABA-B Agonist
- Known off-label uses
- hiccups; alcohol withdrawal
- Contraindications
- hypersensitivity to baclofen; porphyria; peptic ulcer
- Precautions and warnings
- do not stop treatment abruptly; may impair ability to drive or operate machinery
- Minor side effects
- somnolence; fatigue; dizziness; nausea
- Moderate side effects
- muscle weakness; confusional state; headache; constipation
- Dosage forms
- Tablet; Oral solution
- Administration route
- Oral use
- Patient summary
- Designed to relieve muscle spasms to support motor function.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Novartis
- Onset Time
- 1–2 hours
- Duration
- 4–8 hours
- Storage instructions
- Store below 25°C in a dry place.
- Drug interactions
- alcohol; central nervous system depressants; antihypertensives
- Age restrictions
- Use with caution in children.
Serious side effects
respiratory depression, requires immediate medical attention; hallucinations, requires immediate medical attention
Mechanism of action
Activates GABA-B receptors in the spinal cord, which inhibits excitatory neurotransmitters to reduce skeletal muscle spasticity.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary. Breastfeeding: Can be used with caution, monitoring the infant.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Lioresal
Lioresal is the original brand of baclofen, a medication used to manage symptoms associated with multiple sclerosis, spinal cord injury and spinal cord spasm. Supplied as a tablet in 10mg and 25mg strengths, this product is produced by Novartis to aid those with muscle spasticity.
Buying Lioresal online
Lioresal is registered across 14 markets, including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. As a reliable option for muscle management, it is one of the most ordered medications across the region. Generic baclofen, much of it made in India, is a far more affordable solution than the original brand for expats and patients far from a major pharmacy.