Lamprene
The treatment is indicated to alleviate leprosy symptoms and is utilized to support long-term management of mycobacterial infections.
- Category
- Antibiotics
- Active ingredient
- Clofazimine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Capsule, soft
- Strengths
- 50mg
Lamprene details
- Condition
- Leprosy
- Therapeutic class
- Antimycobacterial
- Pharmacological class
- Phenazine derivative
- Contraindications
- hypersensitivity to clofazimine; severe hepatic impairment
- Precautions and warnings
- may cause skin discoloration; monitor for gastrointestinal issues
- Minor side effects
- skin pigmentation; dry skin; nausea
- Moderate side effects
- abdominal ache; diarrhoea
- Dosage forms
- Capsule, soft
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Novartis
- Onset Time
- weeks
- Duration
- months
- Storage instructions
- Store in a cool, dry place.
- Drug interactions
- bedaquiline
- Age restrictions
- Consult specialist for dosage.
- Pregnancy and breastfeeding
- Pregnancy: Use only if necessary. Breastfeeding: Transfer to breast milk occurs.
Serious side effects
splenic infarction, requires immediate medical attention; bowel obstruction, requires immediate medical attention
Patient summary
The treatment is indicated to alleviate leprosy symptoms and is utilized to support long-term management of mycobacterial infections.
Mechanism of action
Clofazimine is a non-bactericidal agent that binds to mycobacterial DNA, inhibiting mycobacterial growth. it also exerts anti-inflammatory effects, which helps mitigate the immune response and discolouration effects in patients.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Lamprene
Lamprene contains Clofazimine, an active ingredient used for the treatment of leprosy. Novartis produces this medicinal product in a 50mg tablet form. The medication works to manage the condition through specific chemical properties, providing necessary support for those undergoing treatment for this bacterial infection.
Lamprene availability in Asia
Lamprene is registered across 13 markets including the Philippines, Indonesia and Taiwan, with availability also in South Korea, Japan and the UAE. As a specialised treatment, it is best used under a doctor’s care to monitor progress and manage side effects. Many residents throughout the region locate this medication through these established networks, for consistent care when living in areas far from a major city clinic.