Bactrim

Trimethoprim

Utilized to target bacterial overgrowth to relieve infections.

Category
Antibiotics
Active ingredient
Trimethoprim
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
400/80 · 800/160mg

Bactrim details

Alternative names
Septrin
Therapeutic class
Trimethoprim Antibiotic
Pharmacological class
Dihydrofolate Reductase Inhibitor
Contraindications
hypersensitivity to trimethoprim; severe renal impairment
Precautions and warnings
maintain adequate fluid intake; monitor blood counts during long-term use
Minor side effects
nausea; diarrhoea
Moderate side effects
skin rash; pruritus
Dosage forms
Tablet
Administration route
Oral use
Patient summary
Utilized to target bacterial overgrowth to relieve infections.
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Roche
Onset Time
1–2 hours
Duration
12 hours
Storage instructions
Store at room temperature.
Drug interactions
digoxin; phenytoin
Age restrictions
Use with caution in elderly.
Serious side effects

blood dyscrasias, requires immediate medical attention; stevens-johnson syndrome, requires immediate medical attention

Mechanism of action

Interferes with bacterial folic acid synthesis, stopping the growth and reproduction of bacteria.

Pregnancy and breastfeeding

Pregnancy: Consult doctor; folic acid supplementation may be required. Breastfeeding: Use with caution.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Bactrim

Bactrim is a well-known preparation containing Trimethoprim, used to manage bacterial infection. Sold under the alternative brand Septrin, this medication is produced by Roche in tablet form, available in strengths of 400/80mg and 800/160mg. Patients requiring this class of antibiotic therapy rely on this established product for its consistent formulation.

Bactrim availability in Asia

Bactrim is registered across 13 markets including Singapore, Hong Kong and Thailand, with availability also in Malaysia, the Philippines and Indonesia. While generic Trimethoprim, often produced in India, offers a cost-effective alternative to the original brand, reliable access remains a factor for expats or those residing far from a well-stocked pharmacy. These tablets are best used under a doctor’s care for the management of specific conditions.