Chloromycetin

Chloramphenicol

Utilized to relieve severe bacterial infections, formulated to target bacterial protein synthesis.

Category
Antibiotics
Active ingredient
Chloramphenicol
Supply
Pharmacy
Route
Oral use
Form
Capsule, hard
Strengths
250 · 500mg

Chloromycetin details

Alternative names
Kemicetine
Therapeutic class
Antibiotic
Pharmacological class
Amphenicol Antibiotic
Contraindications
hypersensitivity to chloramphenicol; porphyria; bone marrow depression
Precautions and warnings
monitor blood counts regularly; avoid prolonged use
Minor side effects
blurred vision; nausea
Moderate side effects
diarrhoea; skin rash
Dosage forms
Capsule, hard
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Pfizer
Onset Time
rapid
Duration
course duration
Storage instructions
Store in a cool dry place.
Drug interactions
warfarin; phenytoin
Age restrictions
Use with caution in neonates.
Pregnancy and breastfeeding
Pregnancy: Avoid near term. Breastfeeding: Not recommended.
Serious side effects

aplastic anaemia, requires immediate medical attention; bone marrow suppression, requires immediate medical attention

Patient summary

Utilized to relieve severe bacterial infections, formulated to target bacterial protein synthesis.

Mechanism of action

Chloramphenicol binds to the 50S subunit of the bacterial ribosome, inhibiting the activity of peptidyl transferase, which prevents the formation of peptide bonds and inhibits bacterial protein synthesis.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Chloromycetin

Chloromycetin is an established brand of chloramphenicol, an antibiotic used for severe bacterial infections and typhoid fever. The same active ingredient is also sold as Kemicetine, marketed by Pfizer. Available forms include tablets in strengths of 250mg and 500mg, providing concentrated support for specific health needs.

Chloromycetin availability in Asia

Chloromycetin is registered across 14 markets, including Hong Kong, Thailand and Malaysia, with availability extending to the Philippines, Indonesia and Taiwan. Generic chloramphenicol is often a more accessible option, particularly for expats or patients living in remote areas where finding specific brands can be challenging. Patients should always use this medication under a doctor’s care to ensure appropriate treatment for their condition.