Rifampin Tablets

Rifampicin

Intended to mitigate bacterial load, to target tuberculosis infection.

Category
Antibiotics
Active ingredient
Rifampicin
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
150 · 300 · 450 · 600mg

Rifampin Tablets details

Alternative names
Rifadin; Rimactane
Therapeutic class
Rifamycin Antibiotic
Pharmacological class
Rifamycin
Contraindications
hypersensitivity to rifamycins; jaundice; concurrent use of certain antivirals
Minor side effects
nausea; diarrhoea; red-orange body fluids
Moderate side effects
hepatotoxicity
Dosage forms
Tablet
Administration route
Oral use
Patient summary
intended to mitigate bacterial load, to target tuberculosis infection.
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Sanofi
Onset Time
2–4 hours
Duration
8–12 hours
Storage instructions
Store in a cool, dry place.
Drug interactions
oral contraceptives; warfarin; corticosteroids; antifungals
Age restrictions
Safe for use in children with appropriate weight-based dosage.
Precautions and warnings

may cause orange discoloration of urine and fluids; liver function monitoring required; avoid soft contact lenses

Serious side effects

anaphylaxis, requires immediate medical attention; acute renal failure, requires immediate medical attention

Mechanism of action

Rifampicin inhibits bacterial ribonucleic acid polymerase, thereby suppressing deoxyribonucleic acid-dependent ribonucleic acid synthesis and causing bacterial cell death.

Pregnancy and breastfeeding

Pregnancy: Use only if essential. Breastfeeding: Present in breast milk; monitor infant.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Rifampin Tablets

Rifampin Tablets contain the active ingredient rifampicin, a broad-spectrum antibiotic used in the treatment of tuberculosis and the reduction of meningococcal carriage. This ingredient is also found in brands like Rifadin and Rimactane. Produced by manufacturers such as Sanofi, Rifampin Tablets are supplied in 150mg, 300mg, 450mg, and 600mg strengths.

Rifampin Tablets availability in Asia

Rifampin Tablets are registered across 14 markets, including the Philippines, Indonesia and Taiwan, with access also available in South Korea, Japan and the UAE. Generic rifampicin, often produced in India, serves as an economical alternative to the original brand for people living throughout these areas. As this medication is used for serious health conditions, it is best used under the specific care of a medical professional.