Januvia
Indicated to manage blood glucose levels in adults and formulated to support glycaemic control in type 2 diabetes.
- Category
- Diabetes Management
- Active ingredient
- Sitagliptin
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 50 · 100mg
Januvia details
- Condition
- Type 2 Diabetes Mellitus
- Alternative names
- Xelevia
- Therapeutic class
- Dipeptidyl Peptidase-4 (DPP-4) Inhibitor
- Pharmacological class
- DPP-4 Inhibitor
- Contraindications
- hypersensitivity to sitagliptin; history of pancreatitis
- Minor side effects
- nausea; upper respiratory tract infection
- Moderate side effects
- hypoglycaemia when combined with insulin or sulphonylureas; constipation
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Merck Sharp & Dohme
- Onset Time
- 1–4 hours
- Duration
- 24 hours
- Storage instructions
- Store below 30°C in the original container.
- Drug interactions
- digoxin
- Age restrictions
- Not indicated for patients under 18 years.
Precautions and warnings
monitor for signs of pancreatitis; use with caution in patients with renal impairment
Serious side effects
acute pancreatitis, requires immediate medical attention; bullous pemphigoid, requires immediate medical attention
Patient summary
Indicated to manage blood glucose levels in adults and formulated to support glycaemic control in type 2 diabetes.
Mechanism of action
Sitagliptin works by inhibiting the DPP-4 enzyme, which breaks down incretin hormones. By increasing the levels of these active hormones, it stimulates insulin release when blood sugar is high and lowers glucose production by the liver between meals.
Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Not recommended as it is unknown if sitagliptin is excreted in human milk.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Januvia
Januvia contains sitagliptin, an active ingredient used for the management of type 2 diabetes mellitus. The same compound is also sold under the brand name Xelevia, produced by Merck Sharp & Dohme. It is supplied as a tablet in strengths of 50mg and 100mg to assist in the daily management of blood glucose levels.
Buying Januvia online
Januvia is registered across 14 markets including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. Generic sitagliptin, much of it made in India, is far more affordable than the original brand and provides an accessible option for expats and those living far from a well stocked medical provider. This treatment is one of the most ordered medications across the region and can be purchased online for delivery across these key locations.