Gutron®

Midodrine

Developed for postural hypotension to manage blood pressure stability.

Active ingredient
Midodrine
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
2.5mg

Gutron® details

Alternative names
Bramox
Therapeutic class
Vasopressor
Pharmacological class
Alpha-1 Agonist
Precautions and warnings
monitor blood pressure in supine position; avoid taking late in the day
Minor side effects
piloerection; scalp pruritus; tingling
Moderate side effects
urinary urgency; supine hypertension
Serious side effects
hypertensive crisis, requires immediate medical attention
Dosage forms
Tablet
Administration route
Oral use
Patient summary
developed for postural hypotension to manage blood pressure stability.
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Takeda
Onset Time
20–60 minutes
Duration
2–4 hours
Storage instructions
Store in a cool dry place.
Drug interactions
alpha-blockers; other vasopressors
Age restrictions
Administer strictly as instructed.
Pregnancy and breastfeeding
Pregnancy: Consult a doctor. Breastfeeding: Consult a doctor.
Contraindications

severe organic heart disease; thyrotoxicosis; phaeochromocytoma; urinary retention

Mechanism of action

Gutron works as a vasopressor to treat low blood pressure. It is converted in the body to desglymidodrine, an active metabolite that stimulates alpha-1 adrenergic receptors. This action constricts both arteries and veins, increasing vascular resistance and thereby raising blood pressure to more stable levels.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Gutron®

Gutron® is the Takeda brand of midodrine, used for managing postural hypotension and hypotension. The same active ingredient is also sold as Bramox, supplied as a tablet in 2.5mg strength. As a recognised therapeutic option, it serves individuals who require consistent support for their blood pressure levels throughout the day.

Buying Gutron® online

Gutron® is registered across 14 markets around the world including South Korea, Japan and the UAE, with availability also in Singapore, Hong Kong and Thailand. As one of the more ordered medications for circulation support across the region, generic midodrine alternatives are often preferred for their cost-effectiveness versus the original brand. We provide access to this medication for expats and local residents who may be far from a well-stocked local medical retailer.