Gutron
Midodrine 2.5mg tablets, used in the management of postural hypotension. A prodrug converted to desglymidodrine, an alpha-1 agonist.
- Category
- Heart & Blood Pressure
- Active ingredient
- Midodrine
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2.5mg
Prescription rules on Gutron vary by country.
Gutron details
- Condition
- Hypotension
- Alternative names
- Bramox
- Therapeutic class
- Vasopressor
- Pharmacological class
- Alpha-1 Agonist
- Precautions and warnings
- monitor blood pressure in supine position; avoid taking late in the day
- Minor side effects
- piloerection; scalp pruritus; tingling
- Moderate side effects
- urinary urgency; supine hypertension
- Serious side effects
- hypertensive crisis, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Takeda
- Onset Time
- 20–60 minutes
- Duration
- 2–4 hours
- Storage instructions
- Store in a cool dry place.
- Drug interactions
- alpha-blockers; other vasopressors
- Age restrictions
- Administer strictly as instructed.
- Pregnancy and breastfeeding
- Pregnancy: Consult a doctor. Breastfeeding: Consult a doctor.
Contraindications
severe organic heart disease; thyrotoxicosis; phaeochromocytoma; urinary retention
Patient summary
Midodrine 2.5mg tablets, used in the management of postural hypotension. A prodrug converted to desglymidodrine, an alpha-1 agonist.
Mechanism of action
Gutron works as a vasopressor to treat low blood pressure. It is converted in the body to desglymidodrine, an active metabolite that stimulates alpha-1 adrenergic receptors. This action constricts both arteries and veins, increasing vascular resistance and thereby raising blood pressure to more stable levels.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Gutron
Gutron is the Takeda brand of midodrine, used for managing postural hypotension and hypotension. The same active ingredient is also sold as Bramox, supplied as a tablet in 2.5mg strength. As a recognised therapeutic option, it serves individuals who require consistent support for their blood pressure levels throughout the day.
Buying Gutron online
Gutron is registered across 14 markets around the world including South Korea, Japan and the UAE, with availability also in Singapore, Hong Kong and Thailand. As one of the more ordered medications for circulation support across the region, generic midodrine alternatives are often preferred for their cost-effectiveness versus the original brand. We provide access to this medication for expats and local residents who may be far from a well-stocked local medical retailer.