Entresto
Indicated for heart failure to support improved cardiac function.
- Category
- Heart & Blood Pressure
- Active ingredients
- Sacubitril · Valsartan
- Supply
- Rx
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 97/103mg
Entresto details
- Condition
- Chronic Heart Failure
- Therapeutic class
- Angiotensin Receptor-Neprilysin Inhibitor (ARNI)
- Pharmacological class
- Neprilysin inhibitor; Sartan
- Precautions and warnings
- monitor blood pressure and renal function; risk of angioedema
- Minor side effects
- hypotension; hyperkalaemia; dizziness
- Moderate side effects
- renal impairment; cough
- Serious side effects
- angioedema, requires immediate medical attention
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Patient summary
- indicated for heart failure to support improved cardiac function.
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Novartis
- Onset Time
- 1 hour
- Duration
- 12 hours
- Storage instructions
- Store below 30°C.
- Drug interactions
- ACE inhibitors; potassium-sparing diuretics
- Age restrictions
- Adults only.
- Pregnancy and breastfeeding
- Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications
hypersensitivity to ingredients; history of angioedema; concurrent use with ACE inhibitors; severe hepatic impairment
Mechanism of action
Entresto is a unique combination treatment for chronic heart failure. It works by increasing protective hormones that promote blood vessel relaxation and salt-water excretion, while simultaneously inhibiting an enzyme that would otherwise counteract these positive effects, thus reducing strain on the deteriorating heart muscle.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Entresto
Entresto combines sacubitril and valsartan to assist in the management of chronic heart failure. Novartis manufactures this medication to help improve cardiac function and reduce the risk of hospitalisation. Tablets are available in the 97/103mg strength, providing a standard dose for long-term health maintenance.
Buying Entresto online
Entresto is one of the most frequently ordered medications for heart health, registered across 14 markets including Taiwan, South Korea and Japan. Coverage extends to regions such as the UAE, Singapore and Hong Kong, allowing expats and residents to secure their supply from a distance. Accessing reliable medication online helps patients maintain consistency in their care regardless of their current location across the region.