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Entresto

Sacubitril · Valsartan

Indicated for heart failure to support improved cardiac function.

Active ingredients
Sacubitril · Valsartan
Route
Oral use
Form
Film-coated tablet
Strengths
97/103mg

You will receive a quality generic equivalent, depending on stock.

Prescription rules on Entresto vary by country.

Entresto details

Therapeutic class
Angiotensin Receptor-Neprilysin Inhibitor (ARNI)
Pharmacological class
Neprilysin inhibitor; Sartan
Precautions and warnings
monitor blood pressure and renal function; risk of angioedema
Minor side effects
hypotension; hyperkalaemia; dizziness
Moderate side effects
renal impairment; cough
Serious side effects
angioedema, requires immediate medical attention
Dosage forms
Film-coated tablet
Administration route
Oral use
Patient summary
indicated for heart failure to support improved cardiac function.
Supply category
Prescription only (specially controlled medicine)
Originator
Novartis
Onset Time
1 hour
Duration
12 hours
Storage instructions
Store below 30°C.
Drug interactions
ACE inhibitors; potassium-sparing diuretics
Age restrictions
Adults only.
Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications

hypersensitivity to ingredients; history of angioedema; concurrent use with ACE inhibitors; severe hepatic impairment

Mechanism of action

Entresto is a unique combination treatment for chronic heart failure. It works by increasing protective hormones that promote blood vessel relaxation and salt-water excretion, while simultaneously inhibiting an enzyme that would otherwise counteract these positive effects, thus reducing strain on the deteriorating heart muscle.

What you will receive

Entresto is the originator brand name, made by Novartis. We use it here to identify the medicine only; we are not affiliated with Novartis and do not ship the original Entresto.

  • You receive a generic equivalent: the same active ingredient (Sacubitril / Valsartan) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
  • The exact brand supplied depends on what is in stock at the dispatching warehouse.
  • A regulated generic matches the original ingredient for ingredient by legal standard.

Are all generics really the same? Read the honest answer.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Entresto

Entresto combines sacubitril and valsartan to assist in the management of chronic heart failure. Novartis manufactures this medication to help improve cardiac function and reduce the risk of hospitalisation. Tablets are available in the 97/103mg strength, providing a standard dose for long-term health maintenance.

Buying Entresto online

Entresto is one of the most frequently ordered medications for heart health, registered across 14 markets including Taiwan, South Korea and Japan. Coverage extends to regions such as the UAE, Singapore and Hong Kong, allowing expats and residents to secure their supply from a distance. Accessing reliable medication online helps patients maintain consistency in their care regardless of their current location across the region.