Zyvox
This antibiotic is indicated for serious bacterial infections developed to target resistant organisms and support recovery during acute illness.
- Category
- Antibiotics
- Active ingredient
- Linezolid
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 600mg
Zyvox details
- Conditions
- Pneumonia · Skin and Soft Tissue Infection
- Therapeutic class
- Oxazolidinone Antibiotic
- Pharmacological class
- Oxazolidinone
- Contraindications
- hypersensitivity to linezolid; uncontrolled hypertension
- Minor side effects
- diarrhoea; nausea; headache
- Moderate side effects
- oral candidiasis; peripheral neuropathy; anaemia
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Pfizer
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store at room temperature, protected from moisture and light.
- Drug interactions
- Pseudoephedrine; SSRIs; MAO inhibitors
- Age restrictions
- Use with caution in paediatric patients.
Precautions and warnings
regular blood monitoring recommended; avoid excessive intake of tyramine-rich foods
Serious side effects
severe blood dyscrasias, requires immediate medical attention; serotonin syndrome, requires immediate medical attention
Patient summary
This antibiotic is indicated for serious bacterial infections developed to target resistant organisms and support recovery during acute illness.
Mechanism of action
Linezolid inhibits bacterial protein synthesis by binding to a site on the bacterial 23S ribosomal RNA of the 50S subunit, preventing the formation of the functional 70S initiation complex.
Pregnancy and breastfeeding
Pregnancy: Not recommended unless clearly indicated. Breastfeeding: Discontinue breastfeeding during treatment.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Zyvox
Zyvox is the established brand of linezolid, a medication used to manage pneumonia and skin and soft tissue infection. Produced by Pfizer, this medicine is supplied as a tablet in 600mg strength. It is an antibiotic that works by stopping the growth of specific bacteria that cause these infections.
Zyvox availability in Asia
Zyvox is registered across 14 markets, including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. Generic linezolid, much of it made in India, is far more affordable than the original brand, providing easier access for expats and people living far from a reliable pharmacy. This product is best used under a doctor’s care.