Zyprexa
Indicated to manage schizophrenia and bipolar disorder and to support long-term symptom stability regarding mood regulation.
- Category
- Mental Health
- Active ingredient
- Olanzapine
- Supply
- Rx
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2.5 · 5 · 7.5 · 10 · 15 · 20mg
Zyprexa details
- Conditions
- Schizophrenia · Bipolar Disorder
- Therapeutic class
- Second-Generation Antipsychotic
- Pharmacological class
- Thienobenzodiazepine
- Contraindications
- narrow-angle glaucoma; hypersensitivity to olanzapine
- Precautions and warnings
- monitor blood sugar levels; watch for weight gain; avoid sudden discontinuation
- Minor side effects
- somnolence; weight gain; dizziness
- Moderate side effects
- orthostatic hypotension; elevated prolactin levels; dry mouth
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Eli Lilly
- Onset Time
- 1–2 weeks
- Duration
- Daily
- Storage instructions
- Store at room temperature in original container.
- Drug interactions
- diazepam; alcohol; levodopa
- Age restrictions
- Not recommended for children under 13.
Serious side effects
neuroleptic malignant syndrome, requires immediate medical attention; hyperglycaemia, requires immediate medical attention; tardive dyskinesia, requires immediate medical attention
Patient summary
indicated to manage schizophrenia and bipolar disorder and to support long-term symptom stability regarding mood regulation.
Mechanism of action
Olanzapine acts as an antagonist at both serotonin (5HT2A/2C) and dopamine (D2) receptors. It also exerts effects on muscarinic, histaminic, and adrenergic receptors to stabilize chemical signalling in the brain.
Pregnancy and breastfeeding
Use only if benefit outweighs risk. Breastfeeding: Use with caution; consult a doctor.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Zyprexa
Zyprexa is the brand-name formulation of olanzapine, an antipsychotic treatment used to manage symptoms of schizophrenia and bipolar disorder. Produced by Eli Lilly, the medication is supplied as a tablet in strengths ranging from 2.5mg to 20mg. It is an established option for patients requiring consistent therapeutic support for these conditions.
Zyprexa availability in Asia
Zyprexa is registered across 14 markets including South Korea, Japan and the UAE, with availability also in Singapore, Hong Kong and Thailand. While the original brand is widely recognised, generic olanzapine, often produced in India, offers a more affordable pathway for long-term health management. For expats and people living far from a well-stocked pharmacy, reliable sourcing ensures consistent access to therapy. This medication is best used under the guidance of a doctor.