Zanaflex
Designed to alleviate muscle tightness and hyperactivity, intended to support patients experiencing spasticity associated with neurological conditions by reducing nerve impulses.
- Category
- Pain Management
- Active ingredient
- Tizanidine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2 · 4mg
Zanaflex details
- Condition
- Muscle Spasticity
- Alternative names
- Sirdalud
- Therapeutic class
- Muscle Relaxant
- Pharmacological class
- Alpha-2 Adrenergic Agonist
- Minor side effects
- drowsiness; dizziness; dry mouth; fatigue
- Moderate side effects
- hypotension; bradycardia; elevated liver enzymes
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Novartis
- Onset Time
- 1–2 hours
- Duration
- 3–6 hours
- Storage instructions
- Store below 25°C in a dry place.
- Drug interactions
- ciprofloxacin; fluvoxamine; alcohol
- Age restrictions
- Use with caution in children.
- Pregnancy and breastfeeding
- Pregnancy: consult a specialist. Breastfeeding: use with caution.
Contraindications
hypersensitivity to tizanidine; severe hepatic impairment; concurrent use with strong CYP1A2 inhibitors
Precautions and warnings
may impair ability to drive or operate machinery; monitor blood pressure; use with caution in the elderly
Serious side effects
hallucinations, requires immediate medical attention; severe hypotension, requires immediate medical attention; hepatitis, requires immediate medical attention
Patient summary
Designed to alleviate muscle tightness and hyperactivity, intended to support patients experiencing spasticity associated with neurological conditions by reducing nerve impulses.
Mechanism of action
Tizanidine is a centrally acting alpha-2 adrenergic agonist. It reduces spasticity by increasing presynaptic inhibition of motor neurons. By acting on the spinal cord, it decreases the excitability of muscle neurones, thereby reducing muscle tone without weakening muscle strength.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Zanaflex
Zanaflex contains tizanidine, a common treatment for muscle spasticity. The same active ingredient is also sold as Sirdalud, a well-known brand produced by manufacturers such as Novartis. This medication is supplied as a tablet, available in strengths of 2mg and 4mg.
Buying Zanaflex online
Zanaflex is registered across 13 markets including Singapore, Hong Kong and Thailand, with availability also in Malaysia, the Philippines and Indonesia. Generic tizanidine is often significantly more affordable than the original brand, offering a practical solution for expats and people residing without easy access to a pharmacy. This medication is one of the most ordered muscle relaxants across the region, accessible online with delivery to your location.