Xenical

Orlistat

Product formulated to manage obesity and intended to support weight reduction by inhibiting dietary fat absorption in the digestive tract.

Active ingredient
Orlistat
Supply
Pharmacy
Route
Oral use
Form
Capsule, hard
Strengths
60 · 120mg

Xenical details

Conditions
Obesity · Overweight
Alternative names
Alli
Therapeutic class
Lipase Inhibitor
Pharmacological class
Gastrointestinal Lipase Inhibitor
Known off-label uses
type 2 diabetes mellitus
Contraindications
chronic malabsorption syndrome; cholestasis; pregnancy; breastfeeding
Minor side effects
flatulence; faecal urgency; fatty stools; abdominal pain
Moderate side effects
liquid stools; incontinence
Dosage forms
Capsule, hard
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Cheplapharm
Onset Time
1–2 hours
Duration
variable based on meal
Storage instructions
Store below 25°C in a dry place, protected from sunlight.
Drug interactions
ciclosporin; levothyroxine; amiodarone; warfarin
Age restrictions
For adults only.
Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Not recommended.
Precautions and warnings

maintain adequate intake of fat-soluble vitamins; may cause changes in bowel habits; maintain a balanced diet

Serious side effects

cholelithiasis, requires immediate medical attention; pancreatitis, requires immediate medical attention; hepatitis, requires immediate medical attention

Patient summary

Product formulated to manage obesity and intended to support weight reduction by inhibiting dietary fat absorption in the digestive tract.

Mechanism of action

This medicine acts as a peripheral lipase inhibitor, preventing the body from breaking down and absorbing fats from the diet, which are then eliminated through bowel movements.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Xenical

Xenical is a well-known brand of orlistat, a medicine used to assist with obesity and overweight conditions. The same active ingredient is also marketed under the brand Alli, and it is supplied as a tablet available in 60mg or 120mg strengths. Produced by Cheplapharm, this treatment helps manage weight by reducing the absorption of dietary fat.

Xenical availability in Asia

Xenical is registered across 14 markets including Taiwan, South Korea and Japan, with availability also in the UAE, Singapore and Hong Kong. Generic orlistat, much of it made in India, is far more affordable than the original brand for people across the region. Reliable access to this medicine is useful for expats living far from a reliable pharmacy. As with all treatments, orlistat is best used under a doctor’s care.