Trandate
This medicine is developed to target hypertension and is utilized to alleviate severe high blood pressure in clinical settings.
- Category
- Heart & Blood Pressure
- Active ingredient
- Labetalol
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 50 · 100 · 200mg
You will receive a quality generic equivalent, depending on stock.
Prescription rules on Trandate vary by country.
Trandate details
- Conditions
- Hypertension · Hypertensive Emergency
- Therapeutic class
- Alpha/Beta-blocker
- Pharmacological class
- Non-selective beta-blocker
- Minor side effects
- dizziness; fatigue; tinnitus
- Moderate side effects
- nasal congestion; postural hypotension; ejaculatory failure
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Originator
- Aspen Pharma
- Onset Time
- 1–2 hours
- Duration
- 8–12 hours
- Storage instructions
- Store below 30°C, in original packaging.
- Drug interactions
- verapamil; cimetidine; tricyclic antidepressants
- Age restrictions
- Use with caution in elderly patients.
Contraindications
hypersensitivity to labetalol; second- or third-degree heart block; bradycardia; uncontrolled heart failure; cardiogenic shock
Precautions and warnings
monitor blood pressure continuously; do not stop abruptly; caution in asthma patients
Serious side effects
bradycardia, requires immediate medical attention; heart failure, requires immediate medical attention
Patient summary
This medicine is developed to target hypertension and is utilized to alleviate severe high blood pressure in clinical settings.
Mechanism of action
Labetalol acts as a competitive antagonist of both alpha-1 and non-specific beta-adrenergic receptors. This dual activity causes peripheral vasodilation and reduces cardiac output, effectively lowering systemic blood pressure.
Pregnancy and breastfeeding
Pregnancy: Used in pregnancy for hypertension under strict supervision. Breastfeeding: Excreted in breast milk; monitor infant.
What you will receive
Trandate is the originator brand name, made by Aspen Pharma. We use it here to identify the medicine only; we are not affiliated with Aspen Pharma and do not ship the original Trandate.
- You receive a generic equivalent: the same active ingredient (Labetalol) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Trandate
Trandate is a brand of labetalol, a medication for hypertension and hypertensive emergency. It is supplied as a tablet in strengths of 50, 100, and 200mg. This medication works by relaxing blood vessels to help lower blood pressure and is often used by patients requiring stable cardiovascular control.
Buying Trandate online
Trandate is registered across 14 markets, including Singapore, Hong Kong and Thailand, with availability also in Malaysia, the Philippines and Indonesia. Note that generic labetalol, much of it made in India, is far more affordable than the original brand. As one of the most ordered treatments for blood pressure management across the region, it provides accessible options for expats and people without easy access to a pharmacy.