Thalix

Thalidomide

Formulated to alleviate symptoms of multiple myeloma to support patient stabilization.

Active ingredient
Thalidomide
Supply
Rx
Route
Oral use
Form
Capsule, hard
Strengths
50 · 100mg

Thalix details

Therapeutic class
Immunomodulator
Pharmacological class
Thalidomide analogue
Minor side effects
somnolence; dizziness; peripheral oedema; constipation
Moderate side effects
peripheral neuropathy; neutropenia
Dosage forms
Capsule, hard
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Natco Pharma
Onset Time
3–4 hours
Duration
24 hours
Storage instructions
Store in a safe location and return unused capsules to the pharmacy.
Drug interactions
hormonal contraceptives; alcohol; sedatives
Age restrictions
Not for use in children.
Contraindications

pregnancy; women of childbearing potential unless strict contraceptive measures exist; severe hypersensitivity

Precautions and warnings

requires participation in a mandatory pregnancy prevention programme; monitor for peripheral neuropathy; risk of thrombotic events

Serious side effects

teratogenicity, requires immediate medical attention; venous thromboembolism, requires immediate medical attention

Patient summary

formulated to alleviate symptoms of multiple myeloma to support patient stabilization.

Mechanism of action

The drug exerts immunomodulatory, anti-inflammatory, and anti-angiogenic properties. It alters cytokine production, specifically inhibiting tumour necrosis factor-alpha, and restricts the growth of new blood vessels supplying tumour cells.

Pregnancy and breastfeeding

Pregnancy: Absolute contraindication due to high risk of severe birth defects. Breastfeeding: Not recommended.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Thalix

Thalix contains thalidomide, an active ingredient used to address the effects of multiple myeloma. Manufactured by Natco Pharma, this medication is supplied as a capsule in 50mg and 100mg strengths. It is a well-recognised treatment option for patients who require this specific therapy as part of their health management plan.

Thalix availability in Asia

Thalidomide is registered for use across 13 markets, including Hong Kong, Thailand and Malaysia, with availability extending to the Philippines, Indonesia and Taiwan. Generic thalidomide options commonly provide a more affordable alternative to original brand versions for residents and expats living across these regions. Because of the specific nature of this treatment, it is best used under the direct care and supervision of a doctor.