Pletal
Developed to target intermittent claudication, utilized to alleviate symptoms of peripheral vascular disease.
- Category
- Heart & Blood Pressure
- Active ingredient
- Cilostazol
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 50 · 100mg
Pletal details
- Condition
- Intermittent Claudication
- Therapeutic class
- Antiplatelet Agent
- Pharmacological class
- Phosphodiesterase-3 Inhibitor
- Contraindications
- congestive heart failure; haemostasis disorders; pregnancy
- Precautions and warnings
- use with caution in patients with cardiac disease; monitor for bleeding
- Minor side effects
- headache; diarrhoea; abnormal stools
- Moderate side effects
- tachycardia; palpitations; dizziness
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Otsuka Pharmaceutical
- Onset Time
- 2–4 weeks
- Duration
- 12 hours
- Storage instructions
- Store below 30°C.
- Drug interactions
- clopidogrel; aspirin; erythromycin; omeprazole
- Age restrictions
- Not recommended for children.
- Pregnancy and breastfeeding
- Pregnancy: Contraindicated. Breastfeeding: Not recommended.
Serious side effects
ventricular tachycardia, requires immediate medical attention; intracranial haemorrhage, requires immediate medical attention
Patient summary
Developed to target intermittent claudication, utilized to alleviate symptoms of peripheral vascular disease.
Mechanism of action
Cilostazol inhibits phosphodiesterase-3, resulting in increased cAMP levels, which inhibits platelet aggregation and promotes vasodilation.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Pletal
Pletal is a brand-name formulation of cilostazol, which is used for the management of intermittent claudication. Produced by Otsuka Pharmaceutical, the medication is supplied as tablets in 50mg and 100mg strengths. The active ingredient functions by assisting circulation in the legs, which benefits those who experience discomfort while walking.
Buying Pletal online
Pletal is registered across 13 markets including Thailand, Malaysia and the Philippines, with availability also in Indonesia, Taiwan and South Korea. As a commonly ordered item across the region, generic cilostazol is often chosen for its affordability, with much of the supply manufactured in India. This presents a reliable access point for expats and those located far from major urban areas who require a consistent supply of their medication.