Nocdurna

Desmopressin

Indicated to manage nocturia to alleviate nocturnal polyuria symptoms.

Active ingredient
Desmopressin
Supply
Pharmacy
Route
Sublingual use
Form
Orodispersible tablet
Strengths
0.2mg

Nocdurna details

Alternative names
Desmomelt; DDAVP
Therapeutic class
Vasopressin analogue
Pharmacological class
Antidiuretic agent
Minor side effects
dry mouth; headache; dizziness; nausea
Moderate side effects
peripheral oedema; hyponatraemia
Dosage forms
Orodispersible tablet
Administration route
Sublingual use
Patient summary
Indicated to manage nocturia to alleviate nocturnal polyuria symptoms.
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Ferring Pharmaceuticals
Onset Time
30–60 minutes
Duration
8–12 hours
Storage instructions
Store in original packaging at room temperature.
Drug interactions
Tricyclic antidepressants; NSAIDs; Carbamazepine
Age restrictions
Generally used in adults.
Contraindications

habitual polydipsia; known hyponatraemia; severe bladder dysfunction; moderate to severe renal impairment; cardiac insufficiency

Precautions and warnings

monitor serum sodium levels; restrict fluid intake one hour before and eight hours after administration; caution in elderly patients

Serious side effects

severe hyponatraemia, requires immediate medical attention; convulsions, requires immediate medical attention

Mechanism of action

Desmopressin mimics the action of antidiuretic hormone, increasing water reabsorption in the distal renal tubules and collecting ducts, thus decreasing urine production.

Pregnancy and breastfeeding

Pregnancy: Use with caution. Breastfeeding: Potential for excretion in breast milk; consult a physician.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Nocdurna

Nocdurna is a brand of desmopressin, used to treat nocturia and nocturnal enuresis. The same active ingredient is also sold under names such as Desmomelt and Ddavp. Ferring Pharmaceuticals supplies this medication as a 0.2mg tablet.

Buying Nocdurna online

Nocdurna is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. Expats and residents located away from a local medical provider often prefer the convenience of ordering online. Generic desmopressin, much of which is made in India, is far more affordable than the original brand. It is one of the most ordered items across the region for those managing night-time interruptions.