Eldepryl

Selegiline

Developed to support motor function in Parkinson's disease, utilized to target dopamine degradation and alleviate symptoms of neurological impairment.

Category
Neurology
Active ingredient
Selegiline
Supply
Rx
Route
Oral use
Form
Tablet
Strengths
5 · 10mg

Eldepryl details

Alternative names
Zelapar
Therapeutic class
Monoamine Oxidase B Inhibitor
Pharmacological class
MAO-B inhibitor
Precautions and warnings
do not use with high-tyramine foods; monitor for orthostatic hypotension
Minor side effects
dry mouth; nausea; headache
Moderate side effects
insomnia; dizziness; orthostatic hypotension
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Orion Pharma
Onset Time
2–4 weeks
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
Caffeine; SSRIs; pethidine
Age restrictions
Not for use in children.
Pregnancy and breastfeeding
Use only if benefit outweighs risk.
Contraindications

concurrent use of serotonergic medicines; concurrent use of pethidine; hypersensitivity

Serious side effects

serotonin syndrome, requires immediate medical attention; hypertensive crisis, requires immediate medical attention; hallucinations, requires immediate medical attention

Patient summary

Developed to support motor function in Parkinson's disease, utilized to target dopamine degradation and alleviate symptoms of neurological impairment.

Mechanism of action

Selegiline is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B). By inhibiting this enzyme, it prevents the breakdown of dopamine in the brain, thereby increasing dopamine availability in the synaptic space.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Eldepryl

Eldepryl is a recognised brand of selegiline, an active ingredient used to manage the symptoms of Parkinson’s Disease. The same medication is also available under the brand name Zelapar. Manufactured by Orion Pharma, the product is supplied as a tablet in standard 5mg and 10mg strengths.

Buying Eldepryl online

Eldepryl is registered across 14 markets, including the UAE, Singapore and Hong Kong, with accessibility also in Thailand, Malaysia and the Philippines. For many expats and individuals finding it difficult to source consistent medication locally, ordering online offers a practical route to maintain treatment schedules. Generic selegiline is often more affordable than original brand versions and remains one of the more frequently requested items for patients throughout the region.