Diclegis

Doxylamine · Pyridoxine

Indicated to manage nausea and vomiting of pregnancy to alleviate symptoms.

Active ingredients
Doxylamine · Pyridoxine
Supply
OTC
Route
Oral use
Form
Modified-release tablet
Strengths
10/10mg

Diclegis details

Alternative names
Cariban; Xidona
Therapeutic class
Antihistamine; Vitamin B6 analogue
Pharmacological class
First-generation antihistamine
Precautions and warnings
may cause drowsiness; use caution with anticholinergic conditions
Minor side effects
drowsiness; dry mouth
Moderate side effects
vertigo; blurred vision
Serious side effects
urinary retention, requires immediate medical attention
Dosage forms
Modified-release tablet
Administration route
Oral use
Patient summary
indicated to manage nausea and vomiting of pregnancy to alleviate symptoms.
Supply category
General sale, no prescription needed
Manufacturer
Duchesnay
Onset Time
4–6 hours
Duration
8–12 hours
Storage instructions
Store in a cool, dry place away from direct light.
Drug interactions
alcohol; sedatives; monoamine oxidase inhibitors
Contraindications

hypersensitivity tooxylamine; hypersensitivity to pyridoxine; concurrent use of monoamine oxidase inhibitors

Mechanism of action

The combination acts on the central nervous system to reduce nausea signals by blocking histamine receptors and supplementing vitamin levels crucial for metabolic processes during pregnancy.

Pregnancy and breastfeeding

Pregnancy: clinically proven safe for use under medical supervision. Breastfeeding: consult doctor.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Diclegis

Diclegis is a widely recognised medication containing Doxylamine and Pyridoxine, used to manage nausea and vomiting of pregnancy. The same ingredient combination is also sold under the brand names Cariban and Xidona. Manufactured by Duchesnay, this product is supplied as a 10/10mg tablet designed to provide consistent support throughout the day.

Buying Diclegis online

Diclegis is registered across 13 markets, including the UAE, Singapore and Hong Kong, with availability also in Thailand, Malaysia and the Philippines. As generic alternatives are often more affordable than the original branded version, many patients value the ability to order these tablets online. This has become one of the most ordered medications in our catalogue for expats and residents across the region who require reliable access to their treatment.