Combipres
Utilized to alleviate high blood pressure by stimulating central alpha-2 receptors.
- Category
- Heart & Blood Pressure
- Active ingredient
- Clonidine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 0.1/15g/mg
Combipres details
- Condition
- Hypertension
- Alternative names
- Catapres
- Therapeutic class
- Antihypertensive
- Pharmacological class
- Alpha-2 Adrenergic Agonist
- Contraindications
- severe heart block; hypersensitivity to components
- Precautions and warnings
- do not discontinue treatment abruptly; use with care in renal failure
- Minor side effects
- dry mouth; sedation; dizziness
- Moderate side effects
- constipation; fatigue; bradycardia
- Serious side effects
- severe rebound hypertension, requires immediate medical attention
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Boehringer Ingelheim
- Onset Time
- 30–60 minutes
- Duration
- 6–10 hours
- Storage instructions
- Store in a cool, dry place.
- Drug interactions
- alcohol; beta blockers; sedatives
- Age restrictions
- Not for paediatric use.
- Pregnancy and breastfeeding
- Pregnancy: Use only when clearly necessary. Breastfeeding: Seek medical advice.
Patient summary
utilized to alleviate high blood pressure by stimulating central alpha-2 receptors.
Mechanism of action
Combipres stimulates alpha-2 adrenergic receptors in the brain stem. This activation reduces sympathetic outflow from the central nervous system, resulting in lowered peripheral vascular resistance and lowered heart rate, which effectively decreases blood pressure levels.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Combipres
Combipres is a well-established medication used to manage hypertension. It contains the active ingredient clonidine, which is also commonly sold under the brand name Catapres. Produced by Boehringer Ingelheim, this treatment is available in tablet form in a 0.1/15g/mg strength, offering a consistent option for individuals monitoring their blood pressure levels.
Buying Combipres online
Combipres is registered across 13 markets, including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. As a frequently ordered treatment across the region, it provides a consistent option for expats who need to maintain their medication supplies. Generic clonidine, much of which is produced in India, is far more affordable than the original brand, offering value for residents and expats living far from a well-stocked pharmacy.