Buspar

Buspirone

Utilized to alleviate symptoms of generalized anxiety, this anxiolytic agent is designed to support mood regulation without significant sedative side effects.

Active ingredient
Buspirone
Supply
Rx
Route
Oral use
Form
Tablet
Strengths
5 · 10mg

Buspar details

Therapeutic class
Anxiolytic
Pharmacological class
Azaspirodecanedione
Known off-label uses
major depressive disorder
Minor side effects
dizziness; headache; nausea; lightheadedness
Moderate side effects
insomnia; nervousness; excitement
Serious side effects
serotonin syndrome, requires immediate medical attention
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Bristol-Myers Squibb
Onset Time
1–2 weeks
Duration
4–6 months
Storage instructions
Store below 25°C; keep out of direct light.
Drug interactions
grapefruit; maoi inhibitors; cns depressants
Age restrictions
Not for children under 18 years.
Contraindications

hypersensitivity to buspirone; severe renal impairment; severe hepatic impairment; epilepsy

Precautions and warnings

may impair driving ability; avoid alcohol during treatment; use with caution in elderly patients

Patient summary

Utilized to alleviate symptoms of generalized anxiety, this anxiolytic agent is designed to support mood regulation without significant sedative side effects.

Mechanism of action

Buspirone is a selective serotonin receptor agonist that acts on 5-HT1A receptors. It influences neurotransmitter pathways to help mitigate anxiety without the typical sedative or muscle-relaxant properties of benzodiazepines.

Pregnancy and breastfeeding

Pregnancy: Use only if necessary. Breastfeeding: Caution advised as excretion into milk is unknown.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Buspar

Buspar is the established brand name for Buspirone, a medication used for the management of Generalized Anxiety Disorder. Originally developed by Bristol-Myers Squibb, the medication is supplied as a tablet in strengths of 5mg and 10mg, providing a consistent option for individuals requiring this specific clinical treatment.

Buspar availability in Asia

Buspar is registered across 12 markets including Indonesia, Taiwan and South Korea, with availability also in the UAE, Singapore and Hong Kong. Generic Buspirone, often sourced from India, provides a more affordable alternative for expats and residents living far from local support. Availability varies throughout these regions, and the medication is best used under a doctor’s care for the management of chronic conditions.