Avapro
Indicated to mitigate high blood pressure, formulated to support renal protection in diabetic patients and target angiotensin receptor pathways.
- Category
- Heart & Blood Pressure
- Active ingredient
- Irbesartan
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 150 · 300mg
Avapro details
- Conditions
- Hypertension · Diabetic Nephropathy · Essential Hypertension · Nephropathy in Type 2 Diabetes Mellitus
- Alternative names
- Aprovel
- Therapeutic class
- Angiotensin II Receptor Antagonist
- Pharmacological class
- Sartan
- Minor side effects
- dizziness; fatigue; nausea
- Moderate side effects
- diarrhoea; musculoskeletal pain; tachycardia
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Sanofi
- Onset Time
- 2–4 hours
- Duration
- 24 hours
- Storage instructions
- Store below 30°C in the original carton.
- Drug interactions
- potassium supplements; lithium
- Age restrictions
- Not recommended for children.
- Pregnancy and breastfeeding
- Not to be used in pregnancy; may cause fetal injury.
Contraindications
hypersensitivity to irbesartan; severe hepatic impairment; pregnancy throughout the second and third trimesters
Precautions and warnings
regular blood pressure monitoring recommended; maintain adequate hydration; use with caution in patients with renal stenosis
Serious side effects
hyperkalaemia, requires immediate medical attention; angioedema, requires immediate medical attention
Patient summary
Indicated to mitigate high blood pressure, formulated to support renal protection in diabetic patients and target angiotensin receptor pathways.
Mechanism of action
It selectively antagonises the angiotensin II receptor. This prevents the hormone angiotensin II from binding to its receptors, which leads to vasodilation and reduced secretion of aldosterone, effectively lowering blood pressure.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Avapro
Avapro is a recognised brand of irbesartan, a medication used for the management of hypertension and diabetic nephropathy. The same active ingredient is also sold under the brand name Aprovel, manufactured by Sanofi. These treatment options are supplied as tablets in 150mg and 300mg strengths for the management of blood pressure.
Buying Avapro online
Avapro is registered across 14 markets, including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Indonesia and Taiwan. Generic irbesartan, much of it made in India, is far more affordable than the original brand, offering practical value for expats and people living in areas far from a major pharmacy. These medications remain one of the most ordered options across the region and can be purchased online for delivery to these markets.