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Acne

Acne develops when oil and dead skin cells clog hair follicles, creating whiteheads, blackheads and sometimes deeper, tender nodules. Most common in teenagers, it also affects many adults, particularly along the jaw and chin. The combination of heat and humidity makes blocked pores a year-round problem.

Yasmin

Drospirenone, Ethinylestradiol

3/0.03mg

Drospirenone with ethinylestradiol as a film-coated tablet, a combined oral contraceptive also listed for acne vulgaris. Gonadotropins are suppressed.

From$1.33/ tabletView

Diane 35

Cyproterone, Ethinylestradiol

2/0.035mg

Cyproterone with ethinylestradiol as a film-coated tablet, used in the management of acne and hirsutism. An anti-androgen paired with an oestrogen.

From$1.03/ tabletView

Minomycin

Minocycline

50 · 100mg

Minocycline 50mg and 100mg, as tablets and hard capsules, used for acne vulgaris and bacterial infection. It binds the 30S ribosomal subunit.

From$2.40/ tabletView

Sumycin

Tetracycline

250 · 500mg

Tetracycline 250mg and 500mg, as tablets and hard capsules, used for acne vulgaris and bacterial infection. Bacterial protein synthesis stops.

From$0.25/ tabletView

Vibramycin

Doxycycline

100mg

Doxycycline 100mg capsules and tablets, used for acne vulgaris, chlamydia, Lyme disease and respiratory tract infection. A broad-spectrum tetracycline.

From$1.11/ tabletView

Terramycin

Oxytetracycline

250mg

Oxytetracycline 250mg film-coated tablets, used for acne vulgaris and respiratory tract infection. A broad-spectrum tetracycline taken by mouth.

From$0.40/ tabletView

Minocin

Minocycline

50 · 100mg

Minocycline 50mg and 100mg hard capsules, used for acne vulgaris. A semi-synthetic tetracycline that halts bacterial protein synthesis.

From$2.63/ tabletView

Retin-a Gel

Tretinoin

0.01 · 0.025%

Retin-A Gel is tretinoin at 0.01% and 0.025% in a gel base for acne vulgaris, a vitamin A derivative that speeds turnover of the skin.

From$7.54/ tubeView

Tazorac

Tazarotene

1 · 5%

Tazarotene 1% and 5% cream and gel, applied to the skin for plaque psoriasis and acne vulgaris. A retinoid prodrug converted to tazarotenic acid.

From$30.46/ tubeView

Retin-a Cream

Tretinoin

0.025 · 0.05%

Tretinoin cream at 0.025% and 0.05%, applied for acne vulgaris and photoageing. It normalises keratinisation so microcomedones do not form.

From$12.35/ tubeView

A-ret

Tretinoin

0.1%

A-Ret is topical tretinoin at 0.1%, supplied as a cream and a gel and used for acne vulgaris. The retinoid raises turnover of follicular skin cells.

From$17.00/ tubeView

Aczone

Dapsone

100mg

Dapsone gel applied to the skin, used for acne vulgaris and dermatitis herpetiformis. A sulfone with both bacteriostatic and anti-inflammatory action.

From$0.05/ tabletView

Adapalen

Adapalene

15g

Adapalene gel in a 15g tube, applied to the skin for acne vulgaris. A retinoid-like compound that modulates keratinisation and cell differentiation.

From$14.71/ tubeView

Isotroin

Isotretinoin

10 · 20mg

Isotroin is isotretinoin 10mg and 20mg soft capsules for acne vulgaris and severe cystic acne, a retinoid that cuts sebum at its source.

From$1.17/ tabletView

Renova

Tretinoin

0.025 · 0.05 · 0.1%

Tretinoin cream at 0.025%, 0.05% and 0.1%, applied for acne vulgaris and photoageing. A vitamin A derivative that speeds skin cell turnover.

From$8.50/ tubeView

Azelex

Azelaic Acid

20%

Azelaic acid 20% cream, applied to the skin for acne vulgaris and rosacea. A dicarboxylic acid that is antimicrobial against Cutibacterium acnes.

From$18.13/ tubeView

Key points

  • Acne develops when excess oil and a blocked pore let the bacterium known as Cutibacterium acnes flourish, with hormones amplifying the process.
  • A common misconception blames oily food or poor hygiene, when the real irritant is often harsh scrubbing, which damages the skin barrier.
  • Mild acne often responds to topical retinoids that speed up cell turnover, while more inflamed cases often need an oral antibiotic.
  • Healed spots in darker skin often leave temporary brown marks rather than true scarring.

What is actually driving it

Three factors converge: excess sebum, a blocked follicle and the bacterium Cutibacterium acnes. Hormones amplify all three, which is why breakouts often track the menstrual cycle or periods of high stress. Contrary to a persistent myth, oily food and poor hygiene are not direct causes, and vigorous scrubbing irritates the skin barrier without clearing pores.

How acne is treated

Treatment is matched to severity. Topical tretinoin is a mainstay for mild to moderate acne, speeding cell turnover so pores stay clear. Inflamed acne often requires an oral antibiotic from the antibiotics category, with doxycycline, minocycline and tetracycline all commonly used. For women whose acne has a hormonal pattern, a combined pill containing drospirenone and ethinylestradiol can reduce breakouts significantly. All acne treatments need six to eight weeks to show full results, so consistency matters more than frequent product changes. The full skin care range on ZoneMD covers topical and systemic options.

Marks versus scars

In darker skin tones, healed acne spots frequently leave brown or reddish patches rather than true scars. These are post-inflammatory hyperpigmentation marks. Treating acne early and wearing daily broad-spectrum SPF are the most effective ways to limit how dark and long-lasting those marks become.

Further reading