Adapalen
Indicated to address acne vulgaris to alleviate skin inflammation.
Adapalen details
- Condition
- Acne Vulgaris
- Alternative names
- Differin
- Therapeutic class
- Retinoid
- Pharmacological class
- Retinoid
- Contraindications
- hypersensitivity to adapalene; severe eczema
- Minor side effects
- erythema; skin dryness; skin peeling
- Moderate side effects
- pruritus; sunburn
- Serious side effects
- dermatitis, requires immediate medical attention
- Dosage forms
- Gel
- Administration route
- Cutaneous use
- Patient summary
- Indicated to address acne vulgaris to alleviate skin inflammation.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Galderma
- Onset Time
- 8–12 weeks
- Duration
- Ongoing use
- Storage instructions
- Store below 25°C. Do not freeze.
- Age restrictions
- Use with caution in adolescents.
Precautions and warnings
avoid contact with eyes and mucous membranes; use sun protection as skin may become sensitive; limit concurrent use of other drying skin treatments
Mechanism of action
Adapalene is a retinoid-like compound that modulates keratinization and cellular differentiation. It binds to specific retinoic acid nuclear receptors to exert anti-inflammatory effects and normalize skin cell turnover, reducing comedone formation.
Pregnancy and breastfeeding
Pregnancy: Avoid use. Breastfeeding: Use with caution as safety is not fully established.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Adapalen
Adapalen is a topical retinoid formulation of the active ingredient Adapalene, commonly used to treat Acne Vulgaris. The same medication is widely distributed under brand names such as Differin. Supplied in a 15g tube, this product offers the standard strength required for a consistent routine.
Buying Adapalen online
Adapalen is registered across 14 markets including Hong Kong, Thailand, and Malaysia, with availability extending to the Philippines, Indonesia, and Taiwan. Generic Adapalene, often manufactured in India, provides a significantly more affordable option compared to top-tier brands. Expats and residents across the region frequently order this product online for delivery to areas where finding a local supplier is difficult.