Tapazole
Developed to mitigate excessive thyroid hormone production for clinical stabilization.
- Category
- Thyroid Health
- Active ingredient
- Thiamazole
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 5 · 10mg
Tapazole details
- Condition
- Hyperthyroidism
- Alternative names
- Carbimazole
- Therapeutic class
- Antithyroid Agent
- Pharmacological class
- Thionamide
- Minor side effects
- nausea; rash; arthralgia; headache
- Moderate side effects
- jaundice; pruritus
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Eli Lilly
- Onset Time
- 30–60 minutes
- Duration
- 6–12 hours
- Storage instructions
- Store at room temperature away from direct medical hazard.
- Drug interactions
- warfarin; theophylline
- Age restrictions
- Used with physician supervision in paediatric cases.
Contraindications
hypersensitivity to thionamides; severe hepatic impairment; history of bone marrow disorders
Precautions and warnings
report any signs of infection or sore throat immediately; monitor white blood cell count; use caution in pregnancy
Serious side effects
agranulocytosis, requires immediate medical attention; hepatitis, requires immediate medical attention; vasculitis, requires immediate medical attention
Patient summary
developed to mitigate excessive thyroid hormone production for clinical stabilization.
Mechanism of action
This medication functions by inhibiting the synthesis of thyroid hormones through the blockade of the enzyme thyroid peroxidase. This prevents the iodination of tyrosine residues, effectively reducing the levels of active thyroid hormones in the blood.
Pregnancy and breastfeeding
Pregnancy: Risk associated with first trimester use; doctor consultation essential. Breastfeeding: Use with caution.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Tapazole
Tapazole is a brand name for thiamazole, used to treat hyperthyroidism. The same active ingredient is also sold as Carbimazole, and is available in tablet form in strengths of 5mg and 10mg. Produced by Eli Lilly, this medication is a standard choice for managing thyroid hormone levels for patients internationally.
Buying Tapazole online
Tapazole is one of the most ordered medications for thyroid management across the region. It is registered across 13 markets including Thailand, Malaysia and the Philippines, with availability also in Indonesia, Taiwan and South Korea. This product can be ordered online with delivery across these nations. Generic thiamazole, often manufactured in India, offers an affordable alternative to the original brand, making consistent care accessible for expats and those living far from local sources.