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Furadantin

Nitrofurantoin

Formulated to treat urinary tract infections to mitigate bacterial colonization in the bladder.

Category
Antibiotics
Active ingredient
Nitrofurantoin
Route
Oral use
Form
Tablet
Strengths
50 · 100mg

You will receive a quality generic equivalent, depending on stock.

Prescription rules on Furadantin vary by country.

Furadantin details

Alternative names
Macrobid; Macrodantin
Therapeutic class
Antibacterial; Nitrofuran
Pharmacological class
Nitrofuran Antibiotic
Known off-label uses
urinary tract infection prophylaxis
Minor side effects
nausea; headache; flatulence
Moderate side effects
diarrhoea; abdominal pain
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Onset Time
1–2 hours
Duration
3–7 days
Storage instructions
Store in its original packaging at room temperature away from moisture.
Drug interactions
antacids containing magnesium trisilicate; probenecid
Age restrictions
Suitable for children and adults; dosage adjusted for body weight.
Contraindications

hypersensitivity to nitrofurantoin; anuria; oliguria; renal impairment; g6pd deficiency

Precautions and warnings

may discolour urine; monitor for pulmonary respiratory symptoms; use with caution in elderly patients

Serious side effects

peripheral neuropathy, requires immediate medical attention; pulmonary fibrosis, requires immediate medical attention; hepatitis, requires immediate medical attention

Patient summary

formulated to treat urinary tract infections to mitigate bacterial colonization in the bladder.

Mechanism of action

Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates that inactivate or alter bacterial ribosomal proteins and other macromolecules. This action inhibits aerobic energy metabolism and protein synthesis, resulting in bactericidal activity specifically within the urinary tract.

Pregnancy and breastfeeding

Pregnancy: Can be used if benefits outweigh risks, but avoid at term due to risk of neonatal haemolytic anaemia. Breastfeeding: Can be used with caution during breastfeeding.

What you will receive

Furadantin is the originator brand name, made by Alvogen. We use it here to identify the medicine only; we are not affiliated with Alvogen and do not ship the original Furadantin.

  • You receive a generic equivalent: the same active ingredient (Nitrofurantoin) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
  • The exact brand supplied depends on what is in stock at the dispatching warehouse.
  • A regulated generic matches the original ingredient for ingredient by legal standard.

Are all generics really the same? Read the honest answer.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Furadantin

Furadantin is a brand of nitrofurantoin, an antibiotic used to treat cystitis and urinary tract infection. The same active ingredient is also sold as Macrobid and Macrodantin, supplied as a tablet in 50mg and 100mg strengths.

Furadantin availability in Asia

Furadantin is registered across 14 markets including Thailand, Malaysia and the Philippines, with availability also in Indonesia, Taiwan and South Korea. Generic nitrofurantoin is often far more affordable than the original brand, providing a practical solution for expats and those living at a distance from a well stocked pharmacy. As with all antibiotic therapy, this medication is best used under the guidance of a doctor.