Fosamax

Alendronic Acid

Designed to mitigate bone density loss in osteoporosis, indicated to support bone structural integrity and reduce the risk of fractures.

Category
Bone Health
Active ingredient
Alendronic Acid
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
35 · 70mg

Fosamax details

Condition
Osteoporosis
Alternative names
Fosamax Once Weekly
Therapeutic class
Bisphosphonate
Pharmacological class
Bisphosphonate
Minor side effects
abdominal pain; dyspepsia; musculoskeletal pain
Moderate side effects
oesophageal ulceration; osteonecrosis of the jaw
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Merck Sharp & Dohme
Onset Time
3–6 months
Duration
long term
Storage instructions
Store at room temperature in original packaging.
Drug interactions
Calcium supplements; antacids; iron supplements
Age restrictions
Not indicated for use in children.
Pregnancy and breastfeeding
Not recommended during pregnancy or breastfeeding.
Contraindications

oesophageal abnormalities; inability to stand or sit upright for 30 minutes; hypocalcaemia

Precautions and warnings

must be taken on an empty stomach with a large glass of water; stay upright for at least 30 minutes after taking; maintain adequate calcium and vitamin D intake

Serious side effects

oesophageal perforation, requires immediate medical attention; severe bone pain, requires immediate medical attention; anaphylaxis, requires immediate medical attention

Patient summary

Designed to mitigate bone density loss in osteoporosis, indicated to support bone structural integrity and reduce the risk of fractures.

Mechanism of action

Alendronate is a bisphosphonate that inhibits osteoclast-mediated bone resorption. By binding to hydroxyapatite crystals in bone, it reduces the activity of cells that break down bone tissue, thereby increasing bone mineral density.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Fosamax

Fosamax is the original brand of Alendronic Acid, a widely used treatment for osteoporosis. The same active ingredient is also sold as Fosamax Once Weekly, and is provided as a tablet in strengths of 35mg and 70mg. Manufactured by Merck Sharp & Dohme, this medication is designed to support long-term bone health and density.

Buying Fosamax online

Fosamax is registered across 14 markets including the UAE, Singapore and Hong Kong, with availability also in Thailand, Malaysia and the Philippines. Because generic Alendronic Acid is often produced in India, it is far more affordable than the original brand and remains one of the most ordered options online for expats and residents across these regions. This provides a reliable supply for those living far from a well stocked facility who require consistent access to bone health maintenance.