One-alpha
Indicated for calcium metabolic disorders, utilized to support bone health and alleviate mineral deficiencies by promoting calcium absorption in the gut.
- Category
- Bone Health
- Active ingredient
- Alfacalcidol
- Route
- Oral use
- Form
- Capsule, soft; Oral drops, solution
- Strengths
- 0.25mcg
You will receive a quality generic equivalent, depending on stock.
Prescription rules on One-alpha vary by country.
One-alpha details
- Conditions
- Osteomalacia · Hyperparathyroidism · Hypocalcaemia
- Alternative names
- Etalpha
- Therapeutic class
- Vitamin D Analogue
- Pharmacological class
- Vitamin D3 Analogue
- Contraindications
- hypercalcaemia; metastatic calcification
- Precautions and warnings
- monitor serum calcium levels regularly
- Minor side effects
- nausea; diarrhoea
- Moderate side effects
- hypercalcaemia; hypercalciuria
- Serious side effects
- nephrocalcinosis, requires immediate medical attention
- Dosage forms
- Capsule, soft; Oral drops, solution
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Originator
- Leo Pharma
- Onset Time
- 3–7 days
- Duration
- 24 hours
- Storage instructions
- Store below 25°C. Keep protected from light and moisture.
- Drug interactions
- calcium supplements; magnesium antacids; corticosteroids
- Age restrictions
- Use with caution in children; dose based on clinical response.
Patient summary
Indicated for calcium metabolic disorders, utilized to support bone health and alleviate mineral deficiencies by promoting calcium absorption in the gut.
Mechanism of action
Alfacalcidol is a synthetic analogue of vitamin D that is rapidly converted to calcitriol in the liver. It helps increase the absorption of calcium and phosphate in the intestines, which supports bone mineralization and prevents conditions related to low calcium levels.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly necessary after risk-benefit assessment. Breastfeeding: Should be used with caution as it may pass into milk.
What you will receive
One-alpha is the originator brand name, made by Leo Pharma. We use it here to identify the medicine only; we are not affiliated with Leo Pharma and do not ship the original One-alpha.
- You receive a generic equivalent: the same active ingredient (Alfacalcidol) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About One-alpha
One-alpha is a formulation of Alfacalcidol, which is used to manage Osteomalacia, Hyperparathyroidism and Hypocalcaemia. The same active ingredient is also sold as Etalpha, and it is provided in capsule form in a strength of 0.25mcg. This medication supports patients needing regular, consistent supplementation for their metabolic health.
Buying One-alpha online
One-alpha is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. Alfacalcidol is one of the most ordered medications for bone health across the region, making it accessible for expats and those living far from a well stocked clinic. Generic forms are typically more affordable than established labels, providing reliable access to this treatment when managing health abroad.