Flagyl

Metronidazole

Utilized to target bacterial and protozoal infection to alleviate symptoms and resolve the underlying infection.

Category
Antibiotics
Active ingredient
Metronidazole
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
200 · 400mg

Flagyl details

Therapeutic class
Nitroimidazole Antibiotic
Pharmacological class
Nitroimidazole
Known off-label uses
rosacea
Contraindications
hypersensitivity to metronidazole
Precautions and warnings
may impair ability to drive or operate machinery
Minor side effects
nausea; metallic taste; headache
Moderate side effects
darkened urine; diarrhoea
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Sanofi
Onset Time
1–2 hours
Duration
8–12 hours
Storage instructions
Store at room temperature in a dry, safe location.
Drug interactions
alcohol; warfarin; disulfiram
Age restrictions
Adjust dosage for paediatric patients based on weight.
Serious side effects

peripheral neuropathy, requires immediate medical attention; seizures, requires immediate medical attention

Patient summary

Utilized to target bacterial and protozoal infection to alleviate symptoms and resolve the underlying infection.

Mechanism of action

Metronidazole is a nitroimidazole derivative that disrupts bacterial and protozoal metabolic processes. Once inside the cell, it is reduced, creating intermediates that damage DNA, thereby inhibiting nucleic acid synthesis and causing cell death.

Pregnancy and breastfeeding

Pregnancy: Avoid during the first trimester. Breastfeeding: Suspend breastfeeding during treatment.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Flagyl

Flagyl is a treatment by Sanofi containing the active ingredient metronidazole, used for bacterial infection, protozoal infection and bacterial vaginosis. Supplied as a tablet in strengths of 200mg and 400mg, this medication is a common option for managing these concerns.

Flagyl availability in Asia

Flagyl is registered across 14 markets including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Indonesia and Taiwan. Generic metronidazole, much of it made in India, is far more affordable than the original brand, offering an accessible route to treatment for expats and people living far from established medical support. This medication is best used under a doctor’s care.