Restfine
Utilized to alleviate sleep difficulty and support natural sleep-wake cycles through hormonal regulation.
- Category
- Sleep Management
- Active ingredient
- Melatonin
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 10mg
Restfine details
- Condition
- Insomnia
- Alternative names
- Circadin
- Therapeutic class
- Melatonin Receptor Agonist
- Pharmacological class
- Melatonin Receptor Agonist
- Contraindications
- hypersensitivity to melatonin
- Minor side effects
- headache; nasopharyngitis
- Moderate side effects
- irritability; anxiety; fatigue
- Serious side effects
- anaphylaxis, requires immediate medical attention
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Neurim Pharmaceuticals
- Onset Time
- 1–2 hours
- Duration
- 6–8 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- fluvoxamine; alcohol
- Age restrictions
- Adults only.
- Pregnancy and breastfeeding
- Pregnancy: Seek medical advice. Breastfeeding: Not recommended.
Patient summary
Utilized to alleviate sleep difficulty and support natural sleep-wake cycles through hormonal regulation.
Mechanism of action
Melatonin serves as a chronobiotic, binding to receptors in the suprachiasmatic nucleus to synchronize the sleep-wake cycle and assist in managing disordered sleep.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Restfine
Restfine, produced by Neurim Pharmaceuticals, contains melatonin, a hormone supplement primarily used for managing insomnia. The same active ingredient is also sold as Circadin, supplied as a tablet in 10mg strengths. This supplement supports the body’s natural sleep-wake cycle, helping individuals who struggle with consistent sleep patterns.
Restfine availability in Asia
Restfine is registered across 13 markets including South Korea, Japan and the UAE, with availability also in Singapore, Hong Kong and Thailand. Generic melatonin, often produced in India, provides a more affordable alternative for expats and residents living far from local health resources. While this supplement is useful for sleep regulation, it is best used under a doctor’s care for the most appropriate application.