Periactin

Cyproheptadine

Intended to manage allergic reactions, formulated to alleviate itching and related symptoms by blocking histamine and serotonin receptors.

Active ingredient
Cyproheptadine
Supply
OTC
Route
Oral use
Form
Tablet
Strengths
4mg

Periactin details

Therapeutic class
Antihistamine
Pharmacological class
First-Generation Antihistamine
Known off-label uses
appetite stimulation
Precautions and warnings
may cause significant drowsiness; use with caution when driving
Minor side effects
drowsiness; dry mouth; dizziness
Moderate side effects
blurred vision; constipation; urinary retention
Dosage forms
Tablet
Administration route
Oral use
Supply category
General sale, no prescription needed
Manufacturer
MSD
Onset Time
15–30 minutes
Duration
4–6 hours
Storage instructions
Store below 25°C in a dry place.
Drug interactions
alcohol; MAO inhibitors; sedatives
Age restrictions
Use with caution in children.
Pregnancy and breastfeeding
Pregnancy: avoid. Breastfeeding: avoid.
Contraindications

hypersensitivity to cyproheptadine; narrow-angle glaucoma; urinary retention; elderly; debilitated patients

Serious side effects

anaphylaxis, requires immediate medical attention; seizures, requires immediate medical attention

Patient summary

Intended to manage allergic reactions, formulated to alleviate itching and related symptoms by blocking histamine and serotonin receptors.

Mechanism of action

Cyproheptadine is an antihistamine and antiserotonergic agent. It competes with histamine and serotonin at receptor sites, thereby reducing inflammation and allergic symptoms, while also possessing significant anticholinergic effects.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Periactin

Periactin is the established brand name for cyproheptadine, a histamine antagonist used to treat symptoms of allergic rhinitis and urticaria. Produced by MSD, the medication serves as a reliable option for managing allergic responses. It is supplied as a 4mg tablet, offering a straightforward way to address symptoms throughout the day.

Buying Periactin online

Periactin is registered across 14 markets including Taiwan, South Korea and Japan, with availability also in the UAE, Singapore and Hong Kong. As one of the most ordered therapies for allergies across the region, it is often secured through online services. Generic cyproheptadine, largely produced in India, offers a far more affordable option than the original brand for expats and travellers distant from a well stocked pharmacy.