Loxitane

Loxapine

This medication is formulated to target schizophrenia symptoms and is intended to alleviate cognitive and behavioural disturbances in patients.

Active ingredient
Loxapine
Supply
Rx
Route
Oral use
Form
Tablet
Strengths
10 · 25mg

Loxitane details

Condition
Schizophrenia
Therapeutic class
Typical Antipsychotic
Pharmacological class
Dibenzoxazepine
Minor side effects
sedation; dizziness; dry mouth
Moderate side effects
extrapyramidal symptoms; constipation; blurred vision
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Teva
Onset Time
1–2 hours
Duration
12–24 hours
Storage instructions
Store at room temperature, protected from light and moisture.
Drug interactions
alcohol; central nervous system depressants; epinephrine
Age restrictions
Not indicated for children.
Contraindications

hypersensitivity to loxapine; severe central nervous system depression; history of closed-angle glaucoma; urinary retention; comatose states

Precautions and warnings

risk of tardive dyskinesia; monitor for signs of neuroleptic malignant syndrome; may impair ability to drive or operate machinery

Serious side effects

neuroleptic malignant syndrome, requires immediate medical attention; tardive dyskinesia, requires immediate medical attention

Patient summary

This medication is formulated to target schizophrenia symptoms and is intended to alleviate cognitive and behavioural disturbances in patients.

Mechanism of action

Loxapine is a typical antipsychotic that acts by blocking dopamine D2 receptors in the brain. By inhibiting these pathways, it modulates central nervous system activity, providing relief from the symptoms associated with psychotic disorders like schizophrenia.

Pregnancy and breastfeeding

Pregnancy: Use only if the potential benefit justifies the risk. Breastfeeding: Breastfeeding is not recommended during treatment.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Loxitane

Loxitane is an antipsychotic medication containing loxapine, used in the management of schizophrenia. Produced by Teva, it is supplied as an oral tablet in strengths of 10mg and 25mg. Patients often rely on these specific dosages to maintain their therapeutic routines across different care settings.

Loxitane availability in Asia

Loxitane is registered across 5 global markets, including Hong Kong and the UAE. Generic loxapine, often manufactured in India, offers a more affordable alternative to the original brand for patients requiring steady access. As with all antipsychotic treatments, this medication is best used under the direct care and supervision of a doctor.