Alcohol Dependence

Alcohol dependence is a chronic condition in which the body and mind adapt to regular heavy drinking, making it physically and psychologically difficult to stop. It is distinct from occasional heavy drinking: people with dependence experience cravings, tolerance, and withdrawal symptoms when they cut back or quit. It affects millions of people across Asia, with high rates reported in South Korea, Japan, and parts of Southeast Asia where alcohol is deeply embedded in social culture.

Medicines used to treat Alcohol Dependence

Antabuse

Disulfiram

250 · 500mg

This agent is utilized to support addiction recovery and is indicated to address alcohol consumption by inducing sensitivity.

From $0.62 / tablet View

Revia

Naltrexone

50mg

Formulated to support abstinence in recovery programs to target cravings for substances.

From $4.45 / tablet View

Campral

Acamprosate

333mg

Formulated to target alcohol withdrawal symptoms to mitigate the urge to consume alcohol.

From $0.86 / tablet View

What drives the cycle

Repeated alcohol use alters the brain’s reward and stress circuits, reinforcing the urge to drink while making sobriety feel uncomfortable. Physical dependence develops when the body compensates for alcohol’s sedative effect by ramping up excitatory activity; removing alcohol then triggers withdrawal symptoms ranging from anxiety and tremors to, in severe cases, seizures. This is why abrupt, unsupported stopping can be dangerous, and why medical management matters.

Medicines used in recovery

Several medicines work alongside counselling and lifestyle changes to support long-term abstinence. Disulfiram creates a strong aversive reaction to alcohol, acting as a deterrent. Naltrexone blunts the reward response so that drinking feels less pleasurable, reducing cravings. Acamprosate helps stabilise the brain’s chemistry during extended abstinence, easing the restlessness and anxiety that can trigger relapse. All three are listed in the addiction recovery category.

If you or someone close is experiencing withdrawal symptoms, seek medical attention promptly. Crisis support lines are available in most countries in the region, including Samaritans of Thailand (02 713 6793) and Samaritans Singapore (1800 221 4444).