Tretiva
Designed to target severe acne, this retinoid is indicated to support the reduction of cysts and is utilized to alleviate persistent skin outbreaks.
- Category
- Skin Care
- Active ingredient
- Isotretinoin
- Supply
- Rx
- Route
- Oral use
- Form
- Capsule, soft
- Strengths
- 5 · 10 · 20 · 30mg
Tretiva details
- Conditions
- Severe Acne · Nodulocystic Acne · Severe Cystic Acne
- Alternative names
- Roaccutane; Isotroin
- Therapeutic class
- Retinoid
- Pharmacological class
- Retinoid
- Minor side effects
- dry skin; dry lips; dry eyes; nosebleeds
- Moderate side effects
- myalgia; elevated liver enzymes; hypertriglyceridaemia
- Dosage forms
- Capsule, soft
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Intas Pharmaceuticals
- Onset Time
- 2–4 weeks
- Duration
- 4–6 months
- Storage instructions
- Store below 25°C in original packaging.
- Drug interactions
- vitamin a supplements; tetracyclines; st. john's wort
- Age restrictions
- Use with caution in adolescents.
Contraindications
pregnancy; breastfeeding; severe hepatic impairment; hypervitaminosis a; hyperlipidaemia
Precautions and warnings
must avoid pregnancy; avoid blood donation during treatment; avoid excessive sun exposure
Serious side effects
teratogenicity, requires immediate medical attention; depression, requires immediate medical attention; pancreatitis, requires immediate medical attention
Patient summary
Designed to target severe acne, this retinoid is indicated to support the reduction of cysts and is utilized to alleviate persistent skin outbreaks.
Mechanism of action
Isotretinoin reduces sebaceous gland activity and size, inhibits keratinization, and modulates inflammation, significantly decreasing the production of sebum that contributes to acne.
Pregnancy and breastfeeding
Pregnancy: Strictly contraindicated; high risk of severe birth defects. Breastfeeding: Contraindicated.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Tretiva
Tretiva contains isotretinoin, an active ingredient used to manage severe acne, including nodulocystic and severe cystic acne. Common brand names for this same ingredient include Roaccutane and Isotroin. Intas Pharmaceuticals supplies the medication in tablet form with strengths ranging from 5mg, 10mg, 20mg to 30mg.
Buying Tretiva online
Tretiva is registered across 13 markets, including Malaysia, the Philippines and Indonesia, with availability also in Taiwan, South Korea and Japan. Generic isotretinoin, much of it made in India, is far more affordable than the original brand, creating a reliable access point for expats and people living far from a well stocked nearby pharmacy. This is one of the most ordered treatments available throughout the region.