Florinef
Formulated to alleviate adrenal insufficiency by replacing deficient mineralocorticoids.
- Category
- Hormone Therapy
- Active ingredient
- Fludrocortisone
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 100mcg
Florinef details
- Conditions
- Adrenal Insufficiency · Adrenogenital Syndrome
- Therapeutic class
- Mineralocorticoid
- Pharmacological class
- Corticosteroid
- Contraindications
- systemic fungal infections
- Precautions and warnings
- monitor blood pressure; monitor serum potassium; risk of fluid retention
- Minor side effects
- weight gain; oedema
- Moderate side effects
- hypertension; hypokalaemia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Aspen
- Onset Time
- 3–6 hours
- Duration
- 12–24 hours
- Storage instructions
- Store in a refrigerator (2-8°C).
- Drug interactions
- amphotericin b; potassium-depleting diuretics
- Age restrictions
- Use with caution in children.
- Pregnancy and breastfeeding
- Use with caution. Benefit vs risk assessment required.
Serious side effects
congestive heart failure, requires immediate medical attention; severe electrolyte imbalance, requires immediate medical attention
Patient summary
formulated to alleviate adrenal insufficiency by replacing deficient mineralocorticoids.
Mechanism of action
Fludrocortisone acts as a potent synthetic mineralocorticoid, promoting sodium and water retention and increasing urinary potassium excretion.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Florinef
Florinef is the brand name for fludrocortisone, a synthetic corticosteroid used to manage Adrenal Insufficiency and Adrenogenital Syndrome. Produced by Aspen, this medication is presented as a tablet in the 100mcg strength. Synthetic fludrocortisone acts as a mineralocorticoid to help the body maintain fluid and electrolyte balance.
Florinef availability in Asia
Florinef is registered across 14 markets including Taiwan, South Korea and Japan, with availability also in the UAE, Singapore and Hong Kong. While generic fludrocortisone, often manufactured in India, may offer a cost-effective alternative to the original formulation, many patients prefer the consistency of the Aspen product. For expats or others living far from a well stocked pharmacy, consistent access is a priority. This medication is best used under a doctor’s care.