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Cyclopentolate

Cyclopentolate (often branded as Cyclogyl) is used to dilate the pupil and temporarily relax the eye muscles. This medication allows for clear visualization of the back of the eye during specialized screenings and diagnostic assessments. We currently list 1 product for this ingredient, providing sterile formulations for ophthalmic use.

Cyclogyl

Mydriasis, Cycloplegia

1%

Cyclopentolate 1% eye drops, used for mydriasis and cycloplegia. A muscarinic antagonist that widens the pupil and suspends the eye's focusing.

From$4.67/ bottleView

Key points

  • An anticholinergic that blocks acetylcholine signals in the iris and ciliary muscle to widen the pupil and stop the lens from focusing.
  • Its dual effect of pupil dilation and accommodation paralysis lets an eye specialist view internal structures without constant muscle movement disrupting the image.
  • Available as a sterile ophthalmic solution, marketed as Minims Cyclopentolate and Cyclogyl in single-dose and multi-use presentations.

What is Cyclopentolate?

Cyclopentolate is an anticholinergic agent. It works by blocking specific nerve impulses to the eye’s ciliary muscle and iris sphincter. This action is temporary and is utilised widely within the scope of Eye Care to facilitate procedures that require a clear view of the interior structures of the eye.

What Cyclopentolate is used for

This medication is applied during full eye exams to induce Mydriasis, which is the widening of the pupil. It also produces Cycloplegia, the temporary paralysis of the eye’s accommodation muscle. By preventing the lens from changing shape to focus, the eye remains at rest, allowing an ophthalmologist or optometrist to examine the retina and optic nerve without interference from constant muscle movement.

How does Cyclopentolate work?

Cyclopentolate acts on the neurotransmitter acetylcholine to interrupt chemical signals in the eyelid and iris. Because acetylcholine is responsible for constriction, inhibiting it causes the sphincter muscle of the iris to relax, widening the pupil. This effect ensures that the eye remains still during measurement or diagnostic imaging, which is critical for accurate clinical results.

Cyclopentolate brands and forms

Cyclopentolate is distinct in its application, primarily available as a liquid solution. Brands such as Minims Cyclopentolate and Cyclogyl offer sterile, ophthalmic-grade preparations. Patients may find these available in single-dose units or multi-use bottles depending on the manufacturer and the specific requirement for preservation-free application.

Further reading