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Ivabradine

Ivabradine is a medication used to reduce the heart rate in individuals managing specific cardiovascular conditions, most notably chronic heart failure and symptoms of angina. It is available under the brand name Procoralan. This listing highlights the film-coated tablet formulation. For those reviewing options, this page provides details on clinical use and brand availability.

Procoralan

Angina Pectoris

5mg

Ivabradine 5mg film-coated tablets, used in the management of stable angina pectoris. It slows the heart by inhibiting the If current alone.

From$2.28/ tabletView

Key points

  • Lowers heart rate for chronic heart failure and stable angina without affecting how forcefully the heart contracts.
  • Works by blocking the heart’s funny current, an electrical channel in pacemaker cells that sets the pace of each beat.
  • Not suitable alongside persistent atrial fibrillation or other electrical-rhythm-altering medicines, and grapefruit juice can alter its blood concentration.

What is Ivabradine?

Ivabradine is a medication that functions by specifically altering the electrical activity within the heart. It belongs to a specialized group of cardiac treatments within the Heart & Blood Pressure category. The medication allows for better control of heart pacing, which is often a required component of long-term cardiovascular care protocols.

What Ivabradine is used for

The primary use for this medication is in the management of chronic heart failure in patients who have a specific heart rate profile. It is also indicated for the symptomatic treatment of Stable Angina Pectoris. By slowing the heart rate, the medication allows for improved blood filling within the heart chambers, which can improve cardiac performance and reduce the workload on the heart muscle.

How does Ivabradine work?

Ivabradine performs its action by inhibiting the funny current (If), which is a specific ion channel in the heart pacemaker cells. By reducing the frequency of the electrical pulses that trigger each heartbeat, the medication effectively lowers the heart rate without impacting heart contractility or blood pressure. This selective action provides a specific pathway for managing cardiovascular conditions.

Ivabradine brands and forms

Ivabradine is primarily available as a film-coated tablet. The originator brand for this compound is Procoralan. Depending on individual clinical requirements, different dosages may be selected to maintain the target heart rate. Patients should note that tablets should generally be taken during meals to ensure consistent absorption.

Safety overview for Ivabradine

What to check before using this medicine

Ensure that your current heart condition and baseline heart rate are documented before starting this medication. It is not suitable for individuals with certain heart rhythm disturbances, such as persistent atrial fibrillation, or in combination with other potent electrical-altering substances.

Possible reactions and tolerability

Common reactions can include visual disturbances, often described as a temporary brightness in the field of vision, which usually resolves with continued use or cessation. Bradycardia, or a heart rate that drops too low, is a possible effect that requires monitoring.

Interactions and health factors

Ivabradine can interact with grapefruit juice, which may alter the concentration of the medication in your system. Other medications that influence the heart rate or liver enzymes should be reviewed to avoid potential complications. Product labelling and verified clinical sources remain the correct references for specific contraindications, interactions and reactions.

Further reading